Results 201 to 210 of about 29,173,928 (234)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Key factors and practical strategies to strengthen hospital disaster preparedness: a qualitative study in Iran. [PDF]

BMJ Open
Yusefi AR, Sadeghi R, Bahmaei J, Atashbahar O, Dastyar N.   +4 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

SM2-PRE+: A Lightweight Pairing-Free Proxy Re-Encryption Scheme for Secure IoMT Healthcare Data Sharing. [PDF]

Sensors (Basel)
Liu S, Zhu M, Wang XA, Fan Z, Zhou X.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Sex and gender bias in large language models: an old problem at a new scale. [PDF]

BMJ Health Care Inform
Barbati C, Casigliani V, Rizzo C, Odone A.   +3 more
europepmc   +1 more source

Author Correction: CANTAC-seq analysis reveals E2f1 and Otx1 coordinate zygotic genome activation in Xenopus tropicalis. [PDF]

Nat Commun
Cui H, Liang W, Shi Z, Zhang L, Li G, Chen R, Tian C, Gan D, Shi X, Sun Z, Zhu Q, Fang L, Huang H, Hu Y, Chen Y, Chen W.   +15 more
europepmc   +1 more source

Designing the Data Elements for Patient Registry System for Membranous Nephropathy in Isfahan Province. [PDF]

Int J Prev Med
Moeinzadeh F, Motafakeran SH, Mortazavi M, Shahidi S, Ghasemi G.   +4 more
europepmc   +1 more source