Results 91 to 100 of about 5,976,554 (303)

Laboratory Literacy: Surveying Lab Result Interpretations of a Local Patient Population

open access: yesPatient Experience Journal
A patient's independent interpretation of their medical laboratory data has become an unspoken prerequisite in the current age of medicine. In the outpatient setting, it is anecdotally commonplace for patients to receive their lab results before their ...
Jordan Franco, Mark K Fung
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Delivery of interpreting services in UK primary care by population needs: a multisite case study

open access: yesBMJ Public Health
Introduction Interpreting services for patients with no/limited English proficiency are key in healthcare communication and quality of care; yet little evidence exists on interpreting service delivery.
Paramjit Gill   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Development of Deep Learning Medical Imaging Model for Interpreting Pneumonia Diagnosis

open access: yesInternational Transactions on Electrical Engineering and Computer Science
: Pneumonia is still one of the key public health problems, particularly in resource-poor areas like Kisii County in Kenya, where poor diagnostic equipment hinders early diagnosis. In this project, the intention was to develop and evaluate an explainable
Joyce W. Gikandi   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A systematic review of automated International Classification of Diseases coding models using the Medical Information Mart for Intensive Care dataset

open access: yesDigital Health
Objective This study aims to investigate the development of automated International Classification of Diseases (ICD) coding models using the Medical Information Mart for Intensive Care (MIMIC) dataset.
Ying Zhang   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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