Results 81 to 90 of about 5,976,554 (303)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

INTERPRETing to increase access to PSYcho-oncology care (INTERPRET-PSY) for cancer patients with limited English proficiency: study protocol for a pilot randomized controlled trial

open access: yesPilot and Feasibility Studies
Background People with cancer who have limited English proficiency (LEP) are at high risk for poor mental health outcomes in survivorship as they face cultural, linguistic, and mobility-related barriers to accessing psychosocial care.
Florence Lui   +11 more
doaj   +1 more source

Représenter la dimension spatiale des contextes d'exercice des professionnels intervenant auprès des migrants : le cas des interprètes

open access: yesRevue Francophone sur la Santé et les Territoires, 2019
The article comes back on two research projects related to medical and social interpreting. The research is pluridisciplinary and involves geography, sociology and public health.
Anne-Cécile Hoyez   +3 more
doaj   +1 more source

Educational Program Evaluation System in a Medical School [PDF]

open access: yes, 2020
A systematic educational program evaluation system for continuous quality improvement in undergraduate medical education is essential. Monitoring and evaluation (M&E) are two distinct but complementary processes referred to in an evaluation system that ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Multimodal generative AI for interpreting 3D medical images and videos

open access: yesnpj Digital Medicine
This perspective proposes adapting video-text generative AI to 3D medical imaging (CT/MRI) and medical videos (endoscopy/laparoscopy) by treating 3D images as videos. The approach leverages modern video models to analyze multiple sequences simultaneously
Jung-Oh Lee   +4 more
doaj   +1 more source

Two h-Index Benchmarks for Evaluating the Publication Performance of Medical Informatics Researchers

open access: yesJournal of Medical Internet Research, 2012
BackgroundThe h-index is a commonly used metric for evaluating the publication performance of researchers. However, in a multidisciplinary field such as medical informatics, interpreting the h-index is a challenge because researchers tend to have diverse
El Emam, Khaled   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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