Results 171 to 180 of about 2,823,528 (278)

Preceptors training need assessment for medical laboratory professional clinical education programs in Ethiopia. [PDF]

open access: yesPLoS One, 2022
Negesso AE   +5 more
europepmc   +1 more source

Facilitating the access to HIV testing at lower costs: “To the laboratory without prescription” (ALSO), a pilot intervention to expand HIV testing through medical laboratories in France

open access: gold
Karen Champenois   +17 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Benchmarking medical laboratory performance on a global scale. [PDF]

open access: yesFront Public Health
Huf W   +7 more
europepmc   +1 more source

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