Results 151 to 160 of about 2,959,314 (265)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Enrollment Problems and Training Models for Training Postgraduate Students in Clinical Laboratory Diagnosis (Professional Degree) During the “Four Certificates in One” Era in China

open access: yesAdvances in Medical Education and Practice
Ziyi Yan,1,2 Yunhan Fu,1,3 Yali Cui,1,4,5 Linghan Kuang,1,6 Hua Shi,1 Ting Liu,1 Xingxin Liu,1 Yongmei Jiang1,2 1Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Key ...
Yan Z   +7 more
doaj  

Assessment and optimization plan for enhancing public medical laboratory services in the Kyrgyz Republic. [PDF]

open access: yesPLOS Glob Public Health
Sabyrbekova T   +5 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

A case report of medical laboratory confirmation of suspected scabies outbreak at Daara Madina Suwaneh, a quranic school located in Brufut Heights, The Gambia, 2025. [PDF]

open access: yesBMC Infect Dis
Sanyang AM   +11 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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