Results 181 to 190 of about 4,158,488 (347)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Medical laboratory diagnostics in Germany - a status report 2024. [PDF]

Ger Med Sci
Vogeser M, Schumacher T, Bühling F.
europepmc   +1 more source

Medical laboratory accreditation status and associated factors in selected private and government health facilities of Addis Ababa, Ethiopia. [PDF]

Pan Afr Med J, 2023
Tesema M, Sisay A.
europepmc   +1 more source

Electrolyte Content and Permeability of the Erythrocyte in Pemphigus11From the Medical and Dermatological Clinics of the Massachusetts General Hospital and the Fatigue Laboratory, Harvard University, Boston. This investigation was aided by a grant from the Milton Fund, Harvard University and by the Corn Industries Research Foundation.

, 1941
N. B. Kurnick, Walter F. Lever, John H. Talbott   +2 more
openalex   +1 more source

Medical Laboratory Haematology [PDF]

Journal of Clinical Pathology, 1991
openaire   +2 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Climate change and medical laboratory operations: Impacts, challenges, and adaptation strategies: A narrative review. [PDF]

Medicine (Baltimore)
Obeagu EI, Bolo B.
europepmc   +1 more source

Adaptation of medical laboratory scientists to workplace hazards - experiences from the COVID-19 pandemic. [PDF]

Front Public Health, 2022
Wolszczak-Biedrzycka B, Bieńkowska A, Maksymowicz S.   +2 more
europepmc   +1 more source

Medical Virtual Public Services [PDF]

The healthcare enterprises are very disconnected. This paper intends to propose a solution that will provide citizens, businesses and medical enterprises with improved access to medical virtual public services.
Iulia SURUGIU, Manole VELICANU
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