Results 211 to 220 of about 10,544,432 (365)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Awareness and Knowledge of Laboratory Acquired Infections Among Medical Laboratory Workers Across Local Government Areas of Lagos State, Nigeria

open access: yesSokoto Journal of Medical Laboratory Science, 2019
Acquired infections occupy a significant position among all the occupationally acquired infections worldwide. Awareness, nature and mode of acquiring these infections will help both the private medical laboratory workers and policy makers on preventive ...
Adejumo, B.I.G.* , Unachukwu, G.I. , Okungbowa, M.A. , Dimkpa, U. and Adebowale, O.M.
doaj  

An Examination of US Consumer Pet and Veterinary Expenditures, 1980-1999 [PDF]

open access: yes
The veterinary medical profession touches nearly everyone's life, either directly or indirectly. An estimated 58.3% of US households own pets (AVMA, 2002), and most people consume livestock products in the form of meat, dairy products, wool, or leather ...
Black, J. Roy   +2 more
core   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy