Results 221 to 230 of about 40,514 (297)

Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA‐DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset

open access: yesAnnals of Neurology, EarlyView.
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap   +37 more
wiley   +1 more source

Effectiveness of vaccination in patients undergoing dialysis or patients with chronic kidney disease: a systematic review protocol. [PDF]

open access: yesBMJ Open
Karim M   +9 more
europepmc   +1 more source

Tuning Cellular Perception in Pluripotent Stem Cells through Topography, Stiffness, and Patterning

open access: yesAdvanced NanoBiomed Research, EarlyView.
Micro‐ and nanotopographical cues, substrate stiffness, and mechanical patterning synergistically direct pluripotent stem cell fate and function by tuning cellular perception at the biointerface. Pluripotent stem cells (PSCs), comprised of embryonic stem cells and induced PSCs, hold tremendous therapeutic potential.
Yuan Jiang   +7 more
wiley   +1 more source

Gold Nanoclusters as Smart Nanoplatforms for Targeted Cancer Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
A folic acid‐targeted gold nanocluster platform is developed for tumor‐specific delivery and radiofrequency (RF)‐triggered release of doxorubicin. Enhanced uptake, nuclear localization, and therapeutic efficacy are confirmed in 2D and 3D spheroid models.
Samad Mussa Farkhani   +6 more
wiley   +1 more source

Stability and Release Characteristics of Core‐Shell Beads with Emulsion Core Under Gastrointestinal Conditions

open access: yesAdvanced NanoBiomed Research, EarlyView.
A combined emulsion–core‐shell structure system is developed for targeted delivery of lipophilic compounds to the proximal intestine. Using vitamin D3‐loaded sunflower oil emulsions, the core‐shell structure enhances droplet stability, encapsulation efficiency, and gastric protection.
Fariba Malekpour Galogahi   +3 more
wiley   +1 more source

Solvent‐ and Energy‐Free Solid‐State Strategy for Enzyme Encapsulation in ZIF

open access: yesAngewandte Chemie, EarlyView.
A solvent‐ and energy‐free solid‐state strategy is developed for synthesizing enzyme@ZIF biocomposites by directly mixing enzymes with ZIF precursors. Driven by acid–base interactions, the resulting biocomposites show enhanced activity due to multiphase crystalline structure, larger surface area, better electron transfer, and favorable enzyme ...
Zefang Yu   +8 more
wiley   +2 more sources

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