Results 91 to 100 of about 9,094,335 (302)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

EAHIL 2025 Workshop & 42nd Problem Conference of Medical Libraries, Łódź, 9–13 June 2025

Forum Bibliotek Medycznych
EAHIL is an international association bringing together medical librarians and information specialists, which alternately organises annual conferences and workshops dedicated to the challenges of working in the field of library and information science ...
Anna Sikorska, Magdalena Jóźwiak
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Bibliotheken im Fluss

GMS Medizin – Bibliothek – Information, 2015
The focus of the current issue 3/2015 of GMS Medizin – Bibliothek – Information is the annual conference 2015 of the German Medical Libraries Association in Mannheim. The motto of the conference was “Libraries in progress”. The authors in this issue are
Bauer, Bruno
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

An Examination of the Factors Affecting the Adoption of Digital Transformation by Librarians at Medical Universities Based on Rogers' Diffusion of Innovation Theory [PDF]

Taṣvīr-i salāmat
Background. Digital transformation refers to the changes resulting from the implementation of digital technologies across all aspects of human life. This study aims to explore the factors affecting the adoption of digital transformation by librarians at ...
Mohammadreza Azadifar, Afshin Hamdipour, Rasoul Zavaraqi, Hashem Atapour   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

The Application of Cognitive Teaching and Learning Strategies to Instruction in Medical Education [PDF]

, 2020
The purpose of this study was to examine teaching strategies from cognitive learning theory applied to medical education and to present specific applications of the strategies and cases. The results of this study yielded (1) seven teaching strategies and
Korean Medical Education Review (의학교육논단)
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Acceptability of medical digital libraries [PDF]

, 2002
Evidenced-based medicine has increased the importance of quick accessibility to reputable, upto-date information. Web-accessible digital libraries (DLs) on the wards can address the demand for such information.
Blandford, A, Adams, A
core