Results 71 to 80 of about 277,188 (302)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

alles – einfach – sofort: Service in Medizinbibliotheken / all – simply – immediately: service in medical libraries

GMS Medizin – Bibliothek – Information, 2010
The focus of the current issue 3/2010 of GMS Medizin – Bibliothek – Information is the annual conference 2010 of the German Medical Libraries Association in Mainz. The motto of the conference was “all – simply – immediately: service in medical libraries”.
Bauer, Bruno
doaj  

Bibliotheken im Fluss

GMS Medizin – Bibliothek – Information, 2015
The focus of the current issue 3/2015 of GMS Medizin – Bibliothek – Information is the annual conference 2015 of the German Medical Libraries Association in Mannheim. The motto of the conference was “Libraries in progress”. The authors in this issue are
Bauer, Bruno
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Automated user modeling for personalized digital libraries

, 2006
Digital libraries (DL) have become one of the most typical ways of accessing any kind of digitalized information. Due to this key role, users welcome any improvements on the services they receive from digital libraries. One trend used to improve digital
Macredie, R.D., Magoulas, G, Macredie, RD, Chen, SY, Chen, S.Y., Magoulas, George, Frias-Martinez, E, Frias-Martinez, E.   +7 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

An Examination of the Factors Affecting the Adoption of Digital Transformation by Librarians at Medical Universities Based on Rogers' Diffusion of Innovation Theory [PDF]

Taṣvīr-i salāmat
Background. Digital transformation refers to the changes resulting from the implementation of digital technologies across all aspects of human life. This study aims to explore the factors affecting the adoption of digital transformation by librarians at ...
Mohammadreza Azadifar, Afshin Hamdipour, Rasoul Zavaraqi, Hashem Atapour   +3 more
doaj   +1 more source

Revitalization of College Libraries with Computer Assistance [PDF]

, 1995
Availability and utilization in teaching learning process; of up-to-date information on topics dealt in colleges is essential to maintain the quality and relevance of college education. The study observes that presently the college libraries in India are
Raman Nair, R.
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Performance Evaluation of Medical Academic Libraries Based on DEA Approach

, 2022
Medical academic libraries are required to exemplify and quantify the value of their services to their users and parent organizations. Using the Data Envelopment Approach (DEA) technique, this study reports and discusses the efficiency measurement of the
Masoumi, Davoud, Zamani, Zahra, Emamgholipour Sefiddashti, Sara, Najafi, Ali; Tehran university of medical science, Razavi Hajiagha, Seyed Hossein, Sheikhshoaei, Fatemeh   +5 more
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