Results 121 to 130 of about 657,342 (338)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Catalogue of Lewis' Medical and Scientific Library Revised to the end of 1937. Part I. Authors and Titles [PDF]
openalex +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Special Libraries, September 1966 [PDF]
Volume 57, Issue 7https://scholarworks.sjsu.edu/sla_sl_1966/1006/thumbnail ...
Special Libraries Association
core +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Personalgewinnung und -entwicklung in (Medizin-)Bibliotheken
This issue focuses on the topic of “Recruiting and developing staff in (medical) libraries” with a particular focus on training and continuing education programs.
Reimann, Iris
doaj +1 more source
Special Libraries, April 1953 [PDF]
Volume 44, Issue 4https://scholarworks.sjsu.edu/sla_sl_1953/1003/thumbnail ...
Special Libraries Association
core +4 more sources
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source

