Results 111 to 120 of about 7,639,465 (394)
Illustrations from the Wellcome Institute Library: The Royal Army Medical Corps ‘Muniment Collection’ [PDF]
, 1994 Shirley Dixon
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
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Medizinbibliothekarische Bibliografie 2014
GMS Medizin – Bibliothek – Information, 2015 The Medical Librarian’s Bibliography 2014 lists all articles from GMS Medizin – Bibliothek – Information and selected publications relevant to medical librarians from following journals: ABI Technik, Bibliothek Forschung und Praxis, Bibliotheksdienst, B ...
Bauer, Bruno
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
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GMS Medizin – Bibliothek – Information, 2009 The Medical Library (Fachbibliothek Medizin (FBM)) was founded in 1969 as a Department of the Central University Library (Zentralbibliothek), and is located within the grounds of the University Medical Center in Mainz.
Geisel, Heike, Schweizer, Stefanus
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Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
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How to Use a Medical Library: A Guide for Practitioners, Research Workers and Students [PDF]
, 1966 Leslie T. Morton
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
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