Results 161 to 170 of about 7,250,297 (420)
Insights and opinions of readers of the Journal of the Medical Library Association. [PDF]
J Med Libr Assoc, 2022 Akers KG +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Shannon D. Jones, MLS, MEd, AHIP, FMLA, Medical Library Association President, 2022-2023. [PDF]
J Med Libr Assoc, 2022 Bartley K +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
121st Annual Meeting Medical Library Association, Inc. May 10-27, 2021. [PDF]
J Med Libr Assoc, 2022 Pionke JJ, Aaronson EM.
europepmc +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
GMS Medizin – Bibliothek – Information, 2008 Support of PDAs is a matter of course for medical libraries in USA. European medical libraries show interest in this mobile technology but lack knowledge about ways and means to advocate PDA usage.
Dollfuß, Helmut
doaj
The publication fate of abstracts presented at the Medical Library Association conferences. [PDF]
J Med Libr Assoc, 2021 Hinrichs RJ, Ramirez M, Ameen M.
europepmc +1 more source