Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
New Vaccines: How and Why ACIP Makes Vaccine Recommendations; National Library Week at the TMC Library; Basics of Evidence-based Practice, Vol 11. (4) [PDF]
Texas Medical Center Library
core +1 more source
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato +9 more
wiley +1 more source
Operational developments at the <i>Journal of the Medical Library Association</i>: improved production timelines, new policy introduction, and senior editorial team updates. [PDF]
Boruff JT, Kraft M.
europepmc +1 more source
Library Holiday Hours; Public Library Access, Vol 9 (12) [PDF]
Texas Medical Center Library
core +1 more source
Unleashing the Power of Machine Learning in Nanomedicine Formulation Development
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore +7 more
wiley +1 more source
124th Annual Conference, Medical Library Association, Inc., Portland, OR, May 18-21, 20242024 Annual Business Meeting and Presidential Inaugural Address, June 5, 2024. [PDF]
Corcoran KE.
europepmc +1 more source

