Results 41 to 50 of about 1,352,022 (283)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

P-Index, A Novel Algorithm for Bibliometric Analysis [PDF]

open access: yes, 2010
Poster presented at Medical Library Association annual meeting, May 2010Describes an algorithm for bibliographic ...
Spore, Stuart
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Donald A. B. Lindberg, MD, Honorary MLA Member

open access: yesJournal of the Medical Library Association, 2020
Donald Allan Bror Lindberg, MD, director emeritus of the US National Library of Medicine (NLM) and Honorary MLA Member, died on August 17, 2019, in Bethesda, Maryland.
Betsy L. Humphreys, Megan Rosenbloom
doaj   +1 more source

Historical Marker Commemorating Founding of Medical Library Association in Philadelphia Unveiled! [PDF]

open access: yes, 2016
On Wednesday, November 4, 2015, the Pennsylvania Historical and Museum Commission, MLA and the Philadelphia Regional Chapter of MLA unveiled a historical marker commemorating MLA\u27s founding in ...
Kipnis, MSI, Daniel G.
core   +1 more source

A review of professionalism within LIS [PDF]

open access: yes, 2017
Purpose: The purpose of this paper is to examine the nature of professionalism within Library and Information Science (LIS) and in doing so draw comparisons with the education and medicine professions.
Cannon, Paul
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Proceedings, 115th Annual Meeting Medical Library Association, Inc. Austin, TX May 15–20, 2015

open access: yesJournal of the Medical Library Association, 2016
The Medical Library Association (MLA) held its 115th annual meeting in Austin, Texas, May 15–20, 2015, at the Austin Convention Center and Austin Hilton. The meeting theme was ‘‘Librarians without Limits.’’
Nicole Mitchell
doaj   +1 more source

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