Results 61 to 70 of about 6,578,863 (285)

Genomic characterization of ST11-KL25 hypervirulent KPC-2-producing multidrug-resistant Klebsiella pneumoniae from China

iScience
Summary: The global prevalence of ST11 hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) isolates has been increasingly documented, yet genomic characterization of this clone remains insufficiently explored.
Yuting Kang, Chao Xu, Wanting Ma, Qiujie Li, Wei Jia, Pengtao Wang   +5 more
doaj   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Review on textbook «Medical microbiology, virology and immunology». Textbook for the students of higher medical educational establishments / edited by V.P. Shyrobokov. – Vinnytsa: Nova kniha, 2011. – 952 p. with ill., and its edition in Russian «Medical m

Medičnì Perspektivi, 2016
Review on textbook «Medical microbiology, virology and immunology». Textbook for the students of higher medical educational establishments / edited by V.P. Shyrobokov. – Vinnytsa: Nova kniha, 2011. – 952 p.
A. I. Vinnikov
doaj   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Medical Microbiology

Academic Medicine, 1940
Marguerite Bourgeois, Kenneth L. Burdon
  +9 more sources

The Relationship between Medical Students’ Assessment of Standardized Patients and Patient‐Physician Interaction Score [PDF]

, 2019
When standardized patients (SPs) are used for educational purposes, the authenticity of role play and the quality of feedback are essential requirements of SPs.
Korean Medical Education Review (의학교육논단)
core   +1 more source

A Critical Review of Medical Humanities Education Curriculum Development Based on Kern’s Curriculum Development Model [PDF]

, 2020
Medical humanities education (MHE) is as essential as basic medical sciences and clinical medicine education. Despite the importance of MHE, MHE curriculum development (CD) has proven to be challenging.
Korean Medical Education Review (의학교육논단)
core   +1 more source

Underground Signals: The Ecological Power of Root Volatiles

Advanced Science, EarlyView.
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao, Nanli Song, François Verheggen, Meritxell Pérez‐Hedo, Andrea Clavijo McCormick, Antonino Cusumano, Arthur de Fouchier, Bing Wang, Chen‐Zhu Wang, Emmanuelle Jacquin‐Joly, Gary W. Felton, Geoff M. Gurr, Hao Guo, Jiancai Li, Jin Zhang, Li Chen, Manqun Wang, Michele Ricupero, Peng Han, Peng He, Qi Yan, Qingbo Tang, Qingsong Liu, Shiheng An, Xiangbo Kong, Xiaoling Sun, Xueming Ren, Yuanyuan Song, Yang Liu, Yanhui Guo, Yunhe Li, Xiao Sun   +31 more
wiley   +1 more source

Differential mucosal tropism and dissemination of classical and hypervirulent Klebsiella pneumoniae infection

iScience
Summary: Klebsiella pneumoniae (Kp) infection is an important healthcare concern. The ST258 classical (c)Kp strain is dominant in hospital-acquired infections in North America and Europe, while ST23 hypervirulent (hv)Kp prevails in community-acquired ...
Teck-Hui Teo, Nurul N. Ayuni, Michelle Yin, Jun Hao Liew, Jason Q. Chen, Natalia Kurepina, Ravisankar Rajarethinam, Barry N. Kreiswirth, Liang Chen, Pablo Bifani   +9 more
doaj   +1 more source

Buruli Ulcer and Medical Geo-Microbiology

Infection and Drug Resistance, 2022
Aseer Manilal,1 Dagimawie Tadesse,1 Kuzhunellil Raghavanpillai Sabu2 1Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia; 2Department of Chemistry, College of Life Sciences ...
Manilal A, Tadesse D, Sabu KR
doaj