Results 111 to 120 of about 1,336,088 (341)

1666P Non-metastatic cohort of the Italian Association for Medical Oncology (AIOM) guideline application in real-world: Multi-Institutional based survey of adjuvant and first-line pancreatic ductal adenocarcinoma treatment in Italy (GARIBALDI) [PDF]

, 2023
Carmine Pinto, Michèle Milella, Francesca Bergamo, Mariacristina Di Marco, Giovanni Gerardo Cardellino, Luigi Cavanna, Elisa Giommoni, Fable Zustovich, Maria Bonomi, Silvia Bozzarelli, Giovanni Vicario, Elena Parlagreco, Giovanni Luca Frassineti, Marina Macchini, Giulia Orsi, Anna Santoni, L Caldirola, Irene De Simone, Michele Reni   +18 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Scope of services provided to childhood cancer patients by the Brazilian Pediatric Palliative Care Network

Frontiers in Oncology
IntroductionBrazil is a developing and an Upper Middle Income, categorized by the World Bank. Therefore, it is a country that needs a special vision for children with oncological diseases who require Pediatric Palliative Care.
Esther Angélica Luiz Ferreira, Esther Angélica Luiz Ferreira, Cristina Ortiz Sobrinho Valete, Cristina Ortiz Sobrinho Valete, Silvia Maria de Macedo Barbosa, Silvia Maria de Macedo Barbosa, Graziela de Araujo Costa, Graziela de Araujo Costa, Poliana Cristina Carmona Molinari, Poliana Cristina Carmona Molinari, Ana Cristina Pugliese de Castro, Ana Cristina Pugliese de Castro, Simone Brasil de Oliveira Iglesias, Simone Brasil de Oliveira Iglesias, Maycon Rodrigo Sarracini, Maycon Rodrigo Sarracini, Rodrigo Bezerra de Menezes Reiff, Rodrigo Bezerra de Menezes Reiff, Rodrigo Bezerra de Menezes Reiff, Cristina Helena Bruno, Cristina Helena Bruno, Maria Sagrario Gómez-Cantarino, Maria Sagrario Gómez-Cantarino, Ana María Ullán   +23 more
doaj   +1 more source

Impact of an Interactive Contouring Module on Knowledge and Interest in Radiation Oncology Among Pre-Clinical Medical Students: A Randomized Trial [PDF]

, 2017
Pushpa Neppala, Grant Larson, Neil Panjwani, Alex K. Bryant, Michael V. Sherer, James D. Murphy, Erin F. Gillespie   +6 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Surgical assessment of the geriatric oncology patient [PDF]

, 2017
BACKGROUND: The aging population in the United States will correlate with an increased number of cancer diagnoses as cancer is primarily a disease of the elderly.
Lampugnale, Cy Andrew
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Medical Oncology [PDF]

, 2020
Ravin Ratan, Shreyaskumar R. Patel
openaire   +2 more sources

Immune inflammation indicators in anal cancer patients treated with concurrent chemoradiation: training and validation cohort with online calculator (ARC: Anal Cancer Response Classifier) [Corrigendum]

Cancer Management and Research, 2019
Casadei-Gardini A, Montagnani F, Casadei C, et al. Cancer Manag Res. 2019;11:3631–3642. The authors have advised that the affiliations are not correct in the published paper (page 3631).
Casadei-Gardini A, Montagnani F, Casadei C, Arcadipane F, Andrikou K, Aloi D, Prete AA, Zampino MG, Argentiero A, Pugliese G, Martini S, Iorio GC, Scartozzi M, Mistrangelo M, Fornaro L, Cassoni P, Marisi G, Dell'Acqua V, Ravenda PS, Lonardi S, Silvestris N, De Bari B, Ricardi U, Cascinu S, Franco P   +24 more
doaj  

Anaplastic Thyroid Carcinoma versus Metastatic SCC: A Diagnostic Dilemma in a Rare Presentation of Post-Radiation Thyroid Swelling

Indian Journal of Medical and Paediatric Oncology
A 71-year-old male with type 2 diabetes and hypertension was diagnosed with carcinoma of the pyriform fossa in 2019. The biopsy was reported as a moderately differentiated squamous cell carcinoma, and positron emission tomography-computed tomography (PET-
Vrushab Rao, Bhooshan Zade
doaj   +1 more source