B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Referral to Medical Oncology: A Crucial Step in the Treatment of Older Patients with Stage III Colon Cancer [PDF]
RuiLi Luo+4 more
openalex +1 more source
Addressing the Oncologist Shortage in Latin America: Insights From a Survey of Medical Oncology Fellowship Programs. [PDF]
Zegarra-López M+3 more
europepmc +1 more source
The Impact of NUTRItional Status at First Medical Oncology Visit on Clinical Outcomes: The NUTRIONCO Study. [PDF]
Muscaritoli M+19 more
europepmc +1 more source
Images in clinical medicine. Bilateral ovarian dermoid cysts. [PDF]
Boulay, Richard, MD, Podczaski, E
core +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Workforce Trends Among Canadian Medical Oncologists and Medical Oncology Trainees over Two Decades. [PDF]
Fundytus A+4 more
europepmc +1 more source
Twice-daily pain monitoring as standard clinical practice for inpatients at a medical oncology unit: a descriptive study [PDF]
A. Martoni+4 more
openalex +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source