Results 61 to 70 of about 867,834 (298)

Multidisciplinary Oncology Education Among Postgraduate Trainees: Systematic Review

open access: yesJMIR Medical Education
BackgroundUnderstanding the roles and patient management approaches of the entire oncology team is imperative for effective communication and optimal cancer treatment.
Houman Tahmasebi   +8 more
doaj   +1 more source

Becoming a mother of a child with cancer: building motherhood Ser madre de un niño con cáncer: construyendo la relación Tornar-se mãe de criança com câncer: construindo a parentalidade

open access: yesRevista Latino-Americana de Enfermagem, 2008
The present study, which was conducted using the Interpretive Interactionism method, had the objective of understanding the experience of becoming a mother of a child with cancer.
Patrícia Luciana Moreira   +1 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Medical oncology [PDF]

open access: yesMedical Journal of Australia, 2002
Ward, R. L., Hawkins, N. J.
openaire   +3 more sources

35 Mentoring medical students towards oncology: results from a pilot multi-institutional mentorship programme [PDF]

open access: bronze, 2021
Kathrine S Rallis   +10 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Pyrotinib Plus Trastuzumab as an Effective Later-Line Therapeutic Strategy for HER2-Positive Metastatic Colorectal Cancer: Results from a Phase II Study

open access: yesDrug Design, Development and Therapy
Wenwei Yang,1,* Jing Zhang,1,* Guifu Wu,2,* Wen Zhang,1 Aiping Zhou,1 Lin Yang,1 Yongkun Sun1 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of
Yang W   +6 more
doaj  

Supplementum 265: Abstracts of the Swiss Oncology & Hematology Congress (SOHC), November 16-18, 2022

open access: yesSwiss Medical Weekly, 2022
Swiss Society of Medical Oncology   +2 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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