Results 81 to 90 of about 981,832 (295)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Chinese Expert Consensus on Clinical Application and Management of Recombinant Human Granulocyte-Colony Stimulating Factor (2026 Edition)

Zhongliu Fangzhi Yanjiu
Neutropenia is a common hematologic toxicity during antitumor therapy and can induce treatment delays, dose reduction, and even febrile neutropenia (FN), thereby causing poor prognosis.
China Anti-Cancer Association Integrated Oncologic Pharmacy Committee, China Anti-Cancer Association Medical Oncology Professional Committee   +1 more
doaj   +1 more source

Cardio-Oncologic Knowledge of Nurses in the Oncology Service: A Multi-Center Survey in China

Journal of Multidisciplinary Healthcare, 2023
Cuiling Zhang,1,* Ziyan Yang,2,* Rongxin Du,3 Yong Feng,4 Xiaohong Zhang,5 Junyan Zhang6 1Department of Digestive Oncology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical ...
Zhang C, Yang Z, Du R, Feng Y, Zhang X, Zhang J   +5 more
doaj  

Palliative medicine and medical oncology

, 2001
Traditionally, medical oncology and palliative care have been considered two distinct and separate disciplines, both as regards treatment objectives and delivery times.
Amadori D., Maltoni M.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Efficacy of Trastuzumab Deruxtecan in HER2-Positive and HER2-Low Metastatic Breast Cancer: A Real-World Retrospective Cohort Study in China

Breast Cancer: Targets and Therapy
Yuxin Yan,1,2 Yizi Jin,1,2 Mingxi Lin,1,2 Ceng Zeng,1,2 Qing Guo,1,2 Teng Zhou,1,2 Dou Dou Li,3 Jian Zhang1,4 1Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of China; 2Department of Breast and Urinary ...
Yan Y, Jin Y, Lin M, Zeng C, Guo Q, Zhou T, Li DD, Zhang J   +7 more
doaj  

E-Oncology and health portals : instructions and standards for the evaluation, production organisation and use [PDF]

, 2003
In 2002 the Italian Ministry of Health promoted the institution of a network and a web portal, E-oncology (2), for the seven NHS research institutions specialising in oncology (Istituti di Ricovero e Cura a Carattere Scientifico - IRCCS). One of the aims
Cognetti, Gaetana, Cecere, Lucia
core  

Ethical Dilemmas in Gynecologic Oncology—Practice Points for the Oncology Practitioner

, 2012
Gynecologic oncology is a unique field in which physicians frequently become engaged in, and manage, ethical dilemmas. Understanding the features of patients who receive ethics consults is crucial for maintaining continuity of care and identifying areas ...
Gallagher, Colleen M, Schlumbrecht, Matthew P, Chief Administrative Fellow, Department of Gynecologic Oncology and Reproductive Medicine   +2 more
core   +1 more source