Results 71 to 80 of about 867,834 (298)

Efficacy of Trastuzumab Deruxtecan in HER2-Positive and HER2-Low Metastatic Breast Cancer: A Real-World Retrospective Cohort Study in China

Breast Cancer: Targets and Therapy
Yuxin Yan,1,2 Yizi Jin,1,2 Mingxi Lin,1,2 Ceng Zeng,1,2 Qing Guo,1,2 Teng Zhou,1,2 Dou Dou Li,3 Jian Zhang1,4 1Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of China; 2Department of Breast and Urinary ...
Yan Y, Jin Y, Lin M, Zeng C, Guo Q, Zhou T, Li DD, Zhang J   +7 more
doaj  

Pancreatitis Can Present Like Cancer: Lymphoplasmacytic Sclerosing Pancreatitis in a Patient with a History of Gastric Carcinoma

European Journal of Case Reports in Internal Medicine, 2019
Autoimmune pancreatitis has been associated with many syndromes in the presence of increased immunoglobulin levels. IgG4 antibodies are elevated in the context of lymphoplasmacytic sclerosing pancreatitis associated with IgG4-related disease.
Susana Rocha Amaral, Luís Elvas, Tatiana Pereira, Gabriela Sousa, Paula Jacinto   +4 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Scope of services provided to childhood cancer patients by the Brazilian Pediatric Palliative Care Network

Frontiers in Oncology
IntroductionBrazil is a developing and an Upper Middle Income, categorized by the World Bank. Therefore, it is a country that needs a special vision for children with oncological diseases who require Pediatric Palliative Care.
Esther Angélica Luiz Ferreira, Esther Angélica Luiz Ferreira, Cristina Ortiz Sobrinho Valete, Cristina Ortiz Sobrinho Valete, Silvia Maria de Macedo Barbosa, Silvia Maria de Macedo Barbosa, Graziela de Araujo Costa, Graziela de Araujo Costa, Poliana Cristina Carmona Molinari, Poliana Cristina Carmona Molinari, Ana Cristina Pugliese de Castro, Ana Cristina Pugliese de Castro, Simone Brasil de Oliveira Iglesias, Simone Brasil de Oliveira Iglesias, Maycon Rodrigo Sarracini, Maycon Rodrigo Sarracini, Rodrigo Bezerra de Menezes Reiff, Rodrigo Bezerra de Menezes Reiff, Rodrigo Bezerra de Menezes Reiff, Cristina Helena Bruno, Cristina Helena Bruno, Maria Sagrario Gómez-Cantarino, Maria Sagrario Gómez-Cantarino, Ana María Ullán   +23 more
doaj   +1 more source

Orthopedic disorders in children suffering from neuroblastoma with intraspinal extension: the experience of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology, and Immunology

, 2021
А. Н. Ремизов, Е. В. Горохова, D. Yu. Kachanov, O. V. Merishavyan, S. P. Khomyakova, S. S. Ozerov, Г. В. Терещенко, Dmitriy Aleksandrovich Kolbovsky, Yu. N. Likar, С. Р. Варфоломеева, Т. V. Shamanskaya   +10 more
openalex   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Comparison of the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS) in clinical trials supporting US Food and Drug Administration (FDA) approval of orphan vs. non-orphan drugs [PDF]

, 2017
C. Moltó Valiente, Ariadna Tibau, Alberto Ocaña, Arnoud J. Templeton, L.P. del Carpio, Joseph C. Del Paggio, Agustí Barnadas, Christopher M. Booth, Eitan Amir   +8 more
openalex   +1 more source

Brief therapeutic guide to non-small cell lung cancer (NSCLC) from a medical oncology perspective

, 2021
Alexandru Grigorescu, Ciprian Ciobotaru
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source