Results 91 to 100 of about 7,890,226 (262)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

ACCELERATIVE AND RADIONUCLIDE TECHNOLOGIES IN CLINICAL MEDICINE

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
Methods based on accelerative and radionuclide technologies are more and more invading clinical practice of modern medicine. The aim of this review is to demonstrate the role of nuclear physics techniques for treatment and diagnostics of various ...
A. P. Chernyaev, S. M. Varzar'
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

The Syllabus Enhancement for Medical Imaging in Biomedical Electronics

open access: yes, 2009
9th Asia-Oceania Congress of Medical Physics (9th AOCMP)is organized by Thai Medical Physicist Society, 22nd-24th October 2009, The Empress Convention Center, Chiangmai ...
Mohamad, N. F.   +3 more
core  

Physics 422 Spring 2023 Syllabus - Medical Physics [PDF]

open access: yes, 2023
This is the Spring 2023 syllabus for Physics 315, Medical Physics, at ...
Koder, Ronald
core  

Advancing Precision Neurology and Wearable Electrophysiology: A Review on the Pivotal Role of Medical Physicists in Signal Processing, AI, and Prognostic Modeling

open access: yesBiophysica
Medical physicists are transforming physiological measurements and electrophysiological applications by addressing challenges like motion artifacts and regulatory compliance through advanced signal processing, artificial intelligence (AI), and ...
Constantinos Koutsojannis   +2 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Stochastic characterization of chronic ventricular ectopic activity [PDF]

open access: yes, 1986
Thesis (Ph.D.)--Harvard-Massachusetts Institute of Technology Division of Health Science and Technology Program in Medical Engineering and Medical Physics, 1986.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Bibliography: leaves 277-289.by Paul ...
Albrecht, Paul, 1956-
core  

Usando a antimatéria na medicina moderna

open access: yesRevista Brasileira de Ensino de Física
Neste artigo, fazemos uma breve exposição de como um dos conceitos fundamentais da física moderna, a existência de antimatéria, tem aplicação na medicina, na chamada tomografia por emissão de pósitrons (PET na sigla em inglês).
A.C.B. Machado, V. Pleitez, M.C. Tijero
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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