Results 31 to 40 of about 790,793 (333)
Pharmaceutics, 2023 The conventional methods of cancer treatment and diagnosis, such as radiotherapy, chemotherapy, and computed tomography, have developed a great deal. However, the effectiveness of such methods is limited to the possible failure or collateral effects on ...
Simona Tarantino +4 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
South African pilot study: End-to-end radiotherapy and medical physics dosimetry audits
South African Journal of Oncology, 2019 Background: The National Metrology Institute of South Africa (NMISA), as an institute responsible for disseminating traceability, has embarked on establishing a national dosimetry audit programme with assistance from the International Atomic Energy ...
Humbulani V. Maselesele +3 more
doaj +1 more source
Development of Physics Applied to Medicine in the UK, 1945–90 [PDF]
, 2006 Annotated and edited transcript of a Witness Seminar held on 5 July 2005. Introduction by Dr Jeff Hughes.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2006.©The Trustee of the Wellcome Trust, London, 2006.All volumes ...
Christie, DA, Tansey, EM
core
Search for massive rare particles with the SLIM experiment
, 2007 The SLIM experiment is a large array of nuclear track detectors located at the Chacaltaya High Altitude Laboratory (5260 m a.s.l.). The preliminary results from the analysis of ~383 m^2 exposed for 4.07 y are here reported.
Giorgini, M.
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
New Capabilities of the FLUKA Multi-Purpose Code
Frontiers in Physics, 2022 FLUKA is a general purpose Monte Carlo code able to describe the transport and interaction of any particle and nucleus type in complex geometries over an energy range extending from thermal neutrons to ultrarelativistic hadron collisions.
C. Ahdida +44 more
doaj +1 more source
, 2004 The Compact Muon Solenoid (CMS) experiment at LHC features the largest Silicon Strip Tracker (SST) ever build. This device is immersed in a 4T magnetic field and, in conjunction with a Pixel system, it allows the momentum of the charged particles to be ...
Sguazzoni, Giacomo
core +2 more sources