Results 51 to 60 of about 805,649 (283)
The Compact Muon Solenoid (CMS) experiment at LHC features the largest Silicon Strip Tracker (SST) ever build. This device is immersed in a 4T magnetic field and, in conjunction with a Pixel system, it allows the momentum of the charged particles to be ...
Sguazzoni, Giacomo
core +2 more sources
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Solving the Solar Neutrino Problem 2 km Underground -- the Sudbury Neutrino Observatory
The Sudbury Neutrino Observatory (SNO) is capable of measuring simultaneously the flux of electron-type neutrinos and the total flux of all active flavours of neutrinos originating from the Sun. A model-independent test of neutrino flavour transformation
Poon, A. W. P.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
In years the bolus is used as human tissue compensator in treatments of superficial tumors using photons and electrons in the radiotherapy. In order to obtain a low cost and noncommercial bolus, it is proposed in this work to find an optimized bolus ...
Carlla da Motta Oliveira +5 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Re-engineering a nanodosimetry Monte Carlo code into Geant4: software design and first results
A set of physics models for nanodosimetry simulation is being re-engineered for use in Geant4-based simulations. This extension of Geant4 capabilities is part of a larger scale R&D project for multi-scale simulation involving adaptable, co-working ...
Gargioni, E., Grichine, V., Pia, M. G.
core +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Companding technique for high dynamic range measurements using gafchromic films
We propose a methodology to perform dose measurements using gafchromic films which can span several decades of dose levels. The technique is based on a rescaling approach using different films irradiated at different dose levels.
Battum +13 more
core +1 more source

