Results 101 to 110 of about 728,122 (298)

Review Of Medical Physiology

, 1975
vii;ill.;587hal ...
Ganong F.William, Ganong, William F.
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Department of Physiology, Army Medical College, Rawalpindi

Journal of Rawalpindi Medical College, 2014
Background: To determine the frequency and severity of depression in patients on Interferon therapy for chronic hepatitis C Methods: Total 97 diagnosed patients of chronic hepatitis C were enrolled.
Saima Humayun Toor
doaj  

Implementing core concept teaching in an integrated, clinical presentation model medical school curriculum

Advances in Physiology Education
The evolving designs of medical school curricula, coupled with the inherently difficult nature of physiology, can create unique challenges and opportunities for physiology educators as they strive to help students acquire the knowledge and understanding ...
Mary M. Pelkowski, Xiaojun Qi-Lytle, Gabi N. Waite   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Working Draft for Revised Medical Curriculum: Preclinical: Physiology

Detailed Objectives and curricular content in Physiologymedical curriculum, medical education, MBBS, physiology, Health ...
Task Force on Medical Education
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Physiology Educational Research Consortium

, 1998
The Physiology Educational Research Consortium (PERC) is a collaborative research and development effort among 13 physiologists and physiology educators representing 12 post-secondary institutions, ranging from community colleges to medical schools. PERC

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Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Cross-sectional insights into exercise physiology knowledge among medical students in Jordan

SAGE Open Medicine
Objectives: Exercise physiology is a branch of physiology that studies how physical activity and exercise alter the structure and function of living organisms.
Iman Aolymat, Yara Almadani, Majd M. Albarakat, Ayah Khleaf Oleimat, Mass Al-Nsour, Marah E’lemat   +5 more
doaj   +1 more source