Results 11 to 20 of about 351,927 (264)

Crystal structure of (1E,1′E)-4,4′-(9,9-diethyl-9H-fluorene-2,7-diyl)dibenzaldehyde dioxime, C31H28N2O2

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2023
C31H28N2O2, triclinic, P1‾$P\overline{1}$ (no. 2), a = 9.0809(9) Å, b = 9.2626(9) Å, c = 14.8540(15) Å, α = 93.574(8)°, β = 98.554(8)°, γ = 99.558(8)°, V = 99.558(8) Å3, Z = 2, Rgt(F) = 0.0541, wRref(F2) = 0.1424, T = 293(2) K.
Ma Ying-Hong   +4 more
doaj   +1 more source

Baicalein Exerts Anti-Neuroinflammatory Effects by Inhibiting the TLR4-ROS /NF-κB-NLRP3 Inflammasome

open access: yesNatural Product Communications, 2021
Emerging evidence indicates that NOD-like receptor protein 3 (NLRP3) inflammasome-induced inflammation plays a critical role in the pathogenesis of Parkinson’s disease (PD). Baicalein has been considered as a possible option for PD treatment based on its
Wenyu Xin   +7 more
doaj   +1 more source

Crystal structure of 9-bromo-4-(6-methoxypyridin-2-yl)-5,6-dihydrobenzo[h]quinazolin- 2-amine, C18H15BrN4O

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2022
C18H15BrN4O, monoclinic, P21/c (no. 14), a = 10.5097(7) Å, b = 6.6990(5) Å, c = 23.5623(15) Å, β = 92.038(6)°, V = 1657.8(2) Å3, Z = 4, R gt(F) = 0.0393, wR ref(F 2) = 0.0863, T = 150.00(10) K.
Li Wenxuan   +4 more
doaj   +1 more source

Crystal structure and anti-inflammatory activity of (3E,5E)-3,5-bis(2-fluorobenzylidene)-1-((4-fluorophenyl)sulfonyl)piperidin-4-one, C25H18F3NO3S

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2020
C25H18F3NO3S, orthorhombic, Pca21 (no. 29), a = 19.1142(7) Å, b = 11.6722(5) Å, c = 9.2390(3) Å, V = 2061.26(13) Å3, Z = 4, Rgt(F) = 0.0422, wRref(F2) = 0.0974, T = 100.02(10) K.
Zhang Jia-Jing   +5 more
doaj   +1 more source

Crystal structure of (E)-7-methoxy-2-(4-morpholinobenzylidene)-3,4-dihydronaphthalen-1(2H)-one, C22H23NO3

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2023
C22H23NO3, triclinic, P1‾$P\overline{1}$ (no. 2), a = 9.6505(4) Å, b = 9.9712(5) Å, c = 10.0845(4) Å, α = 68.177(4)°, β = 88.106(3)°, γ = 79.234(4)°, V = 884.30(7) Å3, Z = 2, Rgt(F) = 0.0424, wRref(F2) = 0.1150, T = 293 K.
Yuan Xiao-Qian   +3 more
doaj   +1 more source

Crystal structure of (E)-7-bromo-2-(4-methoxybenzylidene)-3,4-dihydronaphthalen-1(2H)-one, C18H15BrO2

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2022
C18H15BrO2, monoclinic, P21/n (no. 14), a = 9.1704(9) Å, b = 16.5309(13) Å, c = 10.3528(12) Å, β = 112.368(12)°, V = 1451.3(3) Å3, Z = 4, R gt(F) = 0.0405, wR ref(F 2) = 0.0677, T = 149.99(10) K.
Zhang Yu-Long   +5 more
doaj   +1 more source

Potential anti-neuroinflammatory NF-кB inhibitors based on 3,4-dihydronaphthalen-1(2H)-one derivatives

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Nuclear factor kappa B (NF-кB) inhibition represents a new therapeutic strategy for the treatment of neuroinflammatory diseases. In this study, a series of 3,4-dihydronaphthalen-1(2H)-one (DHN; 6a-n, 7a-c) derivatives were synthesised and characterised ...
Yue Sun   +6 more
doaj   +1 more source

Crystal structure of (E)-7-bromo-2-(3,5-dimethoxybenzylidene)-3,4-dihydronaphthalen-1(2H)-one, C19H17BrO3

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2022
C19H17BrO3, triclinic, P 1‾ $\overline{1}$ (no. 2), a = 8.2887(7) Å, b = 8.4190(12) Å, c = 13.1164(15) Å, α = 93.634(11)°, β = 90.609(9)°, γ = 118.201(11)°, V = 804.17(18) Å3, Z = 2, R gt(F) = 0.0738, wR ref(F 2) = 0.1614, T = 150 K.
Zhang Yu-Long   +4 more
doaj   +1 more source

Use of antibiotics without medical prescription

open access: yesBrazilian Journal of Infectious Diseases
The inappropriate use of antibiotics for the treatment of infections is a worldwide problem that has implications for the cost of treatment and the development of resistant strains of bacteria. The use of antibiotics should follow specific criteria; they
Dalton Espíndola Volpato   +5 more
doaj   +1 more source

Crystal structure and anti-inflammatory activity of (3E,5E)-3-(2-fluorobenzylidene)-1-((4-acetamidophenyl)sulfonyl)-5-(pyridin-3-ylmethylene)piperidin-4-one-methanol-hydrate (2/1/1), C53H50F2N6O10S2

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2020
C53H50F2N6O10S2, monoclinic, P21/n (no. 14), a = 15.088(5) Å, b = 23.560(9) Å, c = 15.401(6) Å, β = 112.254(5)°, V = 5067(3) Å3, Z = 4, Rgt(F) = 0.0509, wRref(F2) = 0.1336, T = 298(2) K.
Wang An-Qi   +5 more
doaj   +1 more source

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