Results 91 to 100 of about 2,509,536 (335)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

How changing quality management influenced PGME accreditation: a focus on decentralization and quality improvement

BMC Medical Education, 2017
Background Evaluating the quality of postgraduate medical education (PGME) programs through accreditation is common practice worldwide. Accreditation is shaped by educational quality and quality management.
Nesibe Akdemir, Kiki M. J. M. H. Lombarts, Emma Paternotte, Bas Schreuder, Fedde Scheele   +4 more
doaj   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

MedM2G: Unifying Medical Multi-Modal Generation via Cross-Guided Diffusion with Visual Invariant [PDF]

arXiv
Medical generative models, acknowledged for their high-quality sample generation ability, have accelerated the fast growth of medical applications. However, recent works concentrate on separate medical generation models for distinct medical tasks and are restricted to inadequate medical multi-modal knowledge, constraining medical comprehensive ...
arxiv  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Nurses experience increased clinical and organisational competence by working with a medical quality register, RevNatus - a qualitative study. [PDF]

BMC Health Serv Res, 2022
Bjørngaard H, Koksvik HS, Jakobsen B, Grønning K.   +3 more
europepmc   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Factors affecting the number of nonconformities from the assessment of safety in medical laboratory according to ISO 15190:2003

Journal of Associated Medical Sciences, 2016
Background: Bureau of Laboratory Quality Standards established medical laboratory safety accreditation program according to ISO 15190: 2003 in Thailand since May 2013. Nonconformities (NCs) were found from 1 to 18 in each laboratory. Number of NCs may be
Surasak Muenphon, Panadda Wiroonboonpat, Sirimart Kumsai, Maliwan Homchan, Aekkarin Submark, Prompussorn Dissara, Natamol Tianmanee, Dhitiwass Suvagandha, Suthon Vongsheree   +8 more
doaj  

Study of the medical service efficiency of county-level public general hospitals based on medical quality constraints: a cross-sectional study. [PDF]

BMJ Open, 2023
Li J, Guo B, Huang X, Wang H, Zuo G, Lu W.   +5 more
europepmc   +1 more source

A CONTRIBUTION FOR DEFINITE AND KNOWN QUANTITY AND QUALITY IN MINERAL WATERS.Read by title at the Meeting of the Mississippi Valley Medical Association, Oct. 14, 15 and 16, 1891, held at St. Louis, Mo. [PDF]

, 1891
GEO. F. HULBERT
openalex   +1 more source