Results 91 to 100 of about 2,671,946 (314)

The importance of implementing the quality management system and using quality strategies to improve the quality of medical services and increase customer satisfaction [PDF]

, 2021
Anca Madar, Nicoleta Andreea Neacșu
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Factors affecting the number of nonconformities from the assessment of safety in medical laboratory according to ISO 15190:2003

Journal of Associated Medical Sciences, 2016
Background: Bureau of Laboratory Quality Standards established medical laboratory safety accreditation program according to ISO 15190: 2003 in Thailand since May 2013. Nonconformities (NCs) were found from 1 to 18 in each laboratory. Number of NCs may be
Surasak Muenphon, Panadda Wiroonboonpat, Sirimart Kumsai, Maliwan Homchan, Aekkarin Submark, Prompussorn Dissara, Natamol Tianmanee, Dhitiwass Suvagandha, Suthon Vongsheree   +8 more
doaj  

Evaluation of quality management systems implementation in medical diagnostic laboratories benchmarked for accreditation [PDF]

, 2015
Selvi Manickam Tamil, Srinivas Ankanagari   +1 more
openalex   +1 more source

Prevalence and Psychological Impact of Acne on Quality of Life among Undergraduate Medical students of Lahore, Pakistan

, 2021
Ali Raza, Ahmad Munib, Pashmal Yousaf, Ayesha Humayun, Ayesha N. Khalid, Ayeza Riaz, Maham Waseem, Fatima Asad, Fahad Zulfiqar, Awais Ahmad Cheema   +9 more
openalex   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Quality of life in medical students during the COVID-19 pandemic

, 2021
Shastri Motilal, Jordan E. Taylor, Kaveer Sookram, Shivana Sooknanan, Shivana Sooknanan, Joanna Sookoo, Shekeela Stroude, Chelsea Sudama, Tanya Tatiparthi, Hannah M. Thompson   +9 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source