Results 111 to 120 of about 3,103,453 (312)
Quality improvement teaching at medical school: a student perspective
Pooja Nair, Ishani Barai, Sunila Prasad, Karishma Gadhvi Department of Medicine, Imperial College School of Medicine, Imperial College London, London, UK Abstract: Guidelines in the UK require all doctors to actively take part in quality improvement ...
Barai I, Prasad S, Gadhvi K, Nair P
core
Medical care for admitted patients is increasingly reallocated to physician assistants (PAs), because of an increased appreciation of continuity of care, pressure to deliver healthcare efficiently, and local shortages of medical doctors (MDs).
Timmermans, MSc. M.J.C. (Radboud University Medical Center, Scientific Center for Quality of Healthcare (IQ healthcare))
core +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Quality of Medical Care in Hospitals
This study was undertaken as one of a series designed to devise and test indexes of adequacy and economy of service which would be sufficiently objective to be repeatable by different observers. Adequacy of medical care has two essential components: availability of the full range of services in accordance with current concepts and good quality of ...
openaire +3 more sources
The Danish quality database for prehospital emergency medical services
Erika Frischknecht Christensen,1–3 Peter Anthony Berlac,4 Henrik Nielsen,5 Christian Fynbo Christiansen5 1Clinical Institute, Aalborg University, 2Department of Anesthesiology and Intensive Care, Aalborg University Hospital, Aalborg, 3Prehospital ...
Christiansen CF +3 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Data quality: how the flow of data influences data quality in a small to medium medical practice
Data is said to be of a required quality, if the data conforms to a defined specification and this specification correctly reflects its intended use.
De la Harpe, Retha +4 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

