Results 101 to 110 of about 2,509,536 (335)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Individualized approach to the surgical management of fibrous dysplasia of the proximal femur

open access: yesOrphanet Journal of Rare Diseases, 2018
Background Fibrous dysplasia of the proximal femur presents with heterogeneous clinical manifestations dictating different surgical approaches. However, to date there are no clear recommendations to guide the choice of surgical approach and no general ...
Bas C. J. Majoor   +5 more
doaj   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

3D MedDiffusion: A 3D Medical Diffusion Model for Controllable and High-quality Medical Image Generation [PDF]

open access: yesarXiv
The generation of medical images presents significant challenges due to their high-resolution and three-dimensional nature. Existing methods often yield suboptimal performance in generating high-quality 3D medical images, and there is currently no universal generative framework for medical imaging.
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

A new form of the medical record of a patient receiving medical care in inpatient conditions, in a day hospital as a criterion for the quality and safety of medical activity

open access: yesМедицинский вестник Юга России
Objective: to conduct a comparative analysis of the previously valid “Card” with a new form of “Card” filled in for patients receiving medical care in a hospital setting with the focus of the attention of practitioners on the new paragraphs of this ...
S. V. Shlyk   +4 more
doaj   +1 more source

Identifying Critical Errors: Addressing Inhaler Technique in the Context of Asthma Management

open access: yesPulmonary Therapy, 2018
Medication use has always played a highly significant role in the overall management of asthma, with appropriate use being linked to good asthma control.
Sinthia Z. Bosnic-Anticevich   +5 more
doaj   +1 more source

MedTruth: A Semi-supervised Approach to Discovering Knowledge Condition Information from Multi-Source Medical Data [PDF]

open access: yesarXiv, 2018
Knowledge Graph (KG) contains entities and the relations between entities. Due to its representation ability, KG has been successfully applied to support many medical/healthcare tasks. However, in the medical domain, knowledge holds under certain conditions. For example, symptom \emph{runny nose} highly indicates the existence of disease \emph{whooping
arxiv  

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