Results 41 to 50 of about 2,509,536 (335)
Zhongguo cuzhong zazhi运动神经元病（motor neuron disease，MND）是一组神经变性疾病，肌萎缩侧索硬化（amyotrophic lateral sclerosis，ALS）是其主要类型。目前ALS/MND缺乏特效诊疗手段，患者预后差。 ALS/MND虽然较罕见，但目前我国该系列疾病住院患者有快速增长趋势，结合我国实际情况，存在ALS/MND临床医疗质量控制的迫切需求。国家神经系统疾病医疗质量控制中心于2022年设立了MND质控专病组，启动了ALS/MND临床医疗质量控制体系建设。以 ...
HE Ji, FAN Dongsheng
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
卒中医疗质量改进临床研究进展 Progress in Clinical Research of Medical Quality Improvement in Stroke
Zhongguo cuzhong zazhi以促进卒中指南推荐向临床实践转化应用为目标的卒中医疗质量改进成为应对全球卒中疾病负担的优先防控策略。本综述介绍了依托于学习型健康系统理念开展的多层面质量改进代表性研究、卒中再灌注治疗及时性的持续提升策略以及数字化时代背景下辅助卒中全流程质量管理的移动与远程医疗的应用。本文总结了目前卒中医疗质量改进领域的进展与潜在方向，以期为我国卒中医疗质量改进项目设计与开展、卒中医疗质量监测与改进体系建设提供借鉴。 Abstract: The improvement of medical quality in ...
姜晓晴1，2，李子孝1，2，3，4，王拥军1，2，3，4 (JIANG Xiaoqing1,2, LI Zixiao1,2,3,4, WANG Yongjun1,2,3,4 )
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Journal of Cardiothoracic Surgery, 2022 Background The past half century has seen the near eradication of transfusion-associated hazards. Intraoperative cell salvage while widely used still poses significant risks and hazards due to human error.
Masashi Uramatsu +7 more
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Фармакоэкономика, 2022 Objective: to evaluate cost-effectiveness and budget impact of using single and dual chamber implantable cardioverter-defibrillators (ICD) adjunctive to the standard drug therapy (DT) compared to the standard DT alone for the primary and secondary ...
T. O. Bessonova +8 more
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A Review on Security and Privacy of Internet of Medical Things [PDF]
arXiv, 2020 The Internet of Medical Things (IoMT) are increasing the accuracy, reliability, and the production capability of electronic devices by playing a very important part in the industry of healthcare. The available medical resources and services related to healthcare are working to get an interconnection with each other by the digital healthcare system by ...
arxiv
Knowledge AI: New Medical AI Solution for Medical image Diagnosis [PDF]
arXiv, 2021 The implementation of medical AI has always been a problem. The effect of traditional perceptual AI algorithm in medical image processing needs to be improved. Here we propose a method of knowledge AI, which is a combination of perceptual AI and clinical knowledge and experience.
arxiv
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
JaMIE: A Pipeline Japanese Medical Information Extraction System [PDF]
arXiv, 2021 We present an open-access natural language processing toolkit for Japanese medical information extraction. We first propose a novel relation annotation schema for investigating the medical and temporal relations between medical entities in Japanese medical reports.
arxiv
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source