Results 121 to 130 of about 13,696,974 (396)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Useless Med School Notes; Medical Education Through Mnemonics [PDF]

, 2019
BACKGROUND: The volume of content required for synthesis by medical students is immense and continues to grow as more insight and information is added to the existing compendium of medical knowledge.
Miller, Aaron B.
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

How Much Do You Love Grey’s Anatomy? [PDF]

, 2020
Does the prominence of medical Television Shows impact people’s decision to pursue a medical career? We are constantly told that the things we see in media and entertainment influences how we think about things, but not much research has been done ...
Baldwin, Katherine
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Transgender Healthcare Teaching in the Undergraduate Medical School Curriculum [PDF]

, 2018
With increasing recognition of the diverse and specific needs of transgender individuals in a health care setting, lack of knowledge, poor attitudes and prejudice towards transgender patients can result in this population being afraid to access medical ...
Donaldson, A., Ewan, J., Frize, R., Sneddon, S.F.   +3 more
core  

Medical Students’ Perceptions of the Implemented Curriculum at Sinnar Medical School: A Cross-Sectional Study from Sudan

Advances in Medical Education and Practice, 2022
Fadi M Toum Ahmed,1,* Mohammed Mahmmoud Fadelallah Eljack,2,* Hiba Awadelkareem Osman Fadl,3– 5 Abdelrahman Hamza Abdelmoneim Hamza,6,7 Siham Abdalrhman Gsmalseed Mohammed,8 Waddah Adil Taha Muawad,9 Tarig Musa Khaleid Almahi,8 Sara Alameen ...
Toum Ahmed FM, Fadelallah Eljack MM, Osman Fadl HA, Abdelmoneim Hamza AH, Gsmalseed Mohammed SA, Taha Muawad WA, Almahi TMK, Mohamed Ahmed SA, Alameen HF   +8 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Eleven Years of Data on the Jefferson Scale of Empathy-Medical Student Version (JSE-S): Proxy Norm Data and Tentative Cutoff Scores. [PDF]

, 2015
OBJECTIVE: This study was designed to provide typical descriptive statistics, score distributions and percentile ranks of the Jefferson Scale of Empathy-Medical Student version (JSE-S) of male and female medical school matriculants to serve as proxy norm
Gonnella, Joseph S., Hojat, Mohammadreza
core   +1 more source