Results 131 to 140 of about 3,654,618 (260)
iScienceSummary: Intermittent pneumatic compression (IPC) is routinely used after stroke for venous thromboembolism prophylaxis, yet its molecular mechanisms remain elusive.
Shasha Lei +6 more
doaj +1 more source
ビショウ カンキョウ ニオケル テイブンシ HIF-1 ソガイザイ ノ コウ シュヨウ カッセイ ノ カイセキ [PDF]
, 2012 Thesis (Ph. D. in Medical Sciences)--University of Tsukuba, (A), no. 6289, 2012.5.31Offprint. Originally published in: International journal of molecular medicine, v. 29, issue 4, pp. 541-549, 2012Includes bibliographical references (p.
岡本 淳
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Preparing a Better Doctor: the C3 curriculum and OSCE scores [PDF]
, 2017 In 2013, a horizontally integrated 18 month curriculum (C3) for undergraduate medical students, which replaced the traditional 24 month basic sciences curriculum, was implemented at the Virginia Commonwealth University School of Medicine. A retrospective,
Pedram, Kimberly
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Art and Medicine: from anatomic studies to Visual Thinking Strategies [PDF]
, 2015 Over the centuries the collaboration between artists and doctors and the relationship between art and medicine disciplines have been documented. Since the '60s the discipline of medical humanities has been developed in order to enrich the studies in ...
De Santis, Sara +2 more
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Just shamans and healers or indigenous medical systems? A critical discourse analysis of the categories of shamans and healers as constructed by social science texts [PDF]
"Just as even a single sentence has traditionally been taken to imply a whole language so a single discourse implies a whole society." Language and Power, N. Fairclough.
Moreno-Leguizamon, Carlos
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source