A new Journal of Medicine and Medical Sciences
Saudi Journal of Medicine and Medical Sciences, 2013 Abdulaziz Al-Quorain, Hassan Bella
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
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Correction to: Evaluating the Lifelong Learning Approach to Demand-Oriented Research in Student Theses Using the ADDIE Model [PDF]
Journal of Mazandaran University of Medical SciencesAbolghasem Rahmani1, Pooria Gill2, Siavash Moradi3, Atefeh Zabihi Zazoly4, Fattane Amuei5, Adele Rafati6 1 MSc in Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Mazandaran University of Medical Science, Sari, Iran 2 Professor ...
Abolghasem Rahmani +5 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
309 Burden of Anemia and Thrombocytopenia among Acute Leukemia Adult and Adolescent Ethiopians Jemal Alemu 1 Amha Gebremedhin 2, Rawleigh Howe 3 1Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia 2 Department of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia 3 Armauer Hansen Research Institute, Addis Ababa, Ethiopia [PDF]
Jemal Alemu +2 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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Clinical Holistic Medicine: Tools for a Medical Science Based on Consciousness [PDF]
, 2004 Søren Ventegodt +3 more
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PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source