Results 81 to 90 of about 3,788,206 (312)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Elderlies and medical services: demand and utilization in Tehran

open access: yesPayesh, 2002
Objectives: To study demand and utilization of medical services in elderly and their causes. Material & methods: This investigation is a cross sectional study held in Tehran.
Maftoon F   +4 more
doaj  

Managing Medical Services towards Maximizing Active Healthy Life for a Competitive Economy [PDF]

open access: yesRevista de Management Comparat International, 2009
When speaking about profit, good management means everything, but in the same time, without healthy people it could also turn into nothing. And more than this, health is in fact the driving asset and the most valuable one in every domain, in any company,
Magdalena Barbu
doaj  

Special connections: January 14, 1991 [PDF]

open access: yes, 1991
Time-sensitive news update to monthly University Hospital ...
Office of Publication Services, Boston University Medical Center
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The medical information system as a universal tool to improve the efficiency of commercial activities of modern hospital

open access: yesМедицинский вестник Юга России, 2017
In modern conditions the success of a medical institution is determined by its competitiveness. The differences between organizations in terms of medical technology development, technical capabilities and experience of the specialists tend to be aligned.
D. A. Mahnev, N. M. Korzhavchikova
doaj   +1 more source

Special connections: April 12, 1993 [PDF]

open access: yes, 1877
Time-sensitive news update to monthly University Hospital ...
Office of Publication Services, Boston University Medical Center
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Modeling a Process-Oriented System for Ensuring the Guality of Medical Services in the Arctic zone of the Russian Federation

open access: yesМодернизация, инновация, развитие, 2019
Purpose: the main goal is to simulate a process-oriented system for ensuring the quality of medical services in health care facilities in the Arctic zone of the Russian Federation.
K. N. Glazov
doaj   +1 more source

Managing for change: September 11, 1990 v. 1, no. 4 [PDF]

open access: yes, 1990
Bi-weekly newsletter of University Hospital's Change Project, provided to managers at the ...
Boston University Medical Center, Office of Publication Services
core  

Home - About - Disclaimer - Privacy