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Challenges Associated with the Safety Signal Detection Process for Medical Devices

Medical Devices: Evidence and Research, 2021
Josep Pane,1,2 Katia MC Verhamme,1 Dorian Villegas,2 Laura Gamez,3 Irene Rebollo,3 Miriam CJM Sturkenboom4 1Department of Medical Informatics, Erasmus Medical Center, University of Rotterdam, Rotterdam, Netherlands; 2Alcon, Fort Worth, USA; 3Novartis ...
Pane J, Verhamme KMC, Villegas D, Gamez L, Rebollo I, Sturkenboom MCJM   +5 more
doaj   +8 more sources

Deep learning based signal processing and detection for multiple medical devices OFDM systems

Scientific Reports
In general multiple medical devices orthogonal frequency-division multiplexing (OFDM) communication systems, all the interfering medical users are legitimate but will cause disturbance to the desired user.
Haoyu Wang, Yaoping Yu, Xiaoguang Liu, Kun Wei, Wangshu Zhang, Youjie Ye, Yulin Zhou   +6 more
doaj   +3 more sources

Detection and evaluation of signals associated with exposure to individual and combination of medications in pregnancy: a signal detection study protocol [PDF]

BMJ Open, 2023
Introduction Considering the high prevalence of polypharmacy in pregnant women and the knowledge gap in the risk–benefit safety profile of their often-complex treatment plan, more research is needed to optimise prescribing.
Subramanian, Anuradhaa, Lee, Siang, Hemali Sudasinghe, Sudasing, Wambua, Steven, Phillips, Katherine, Singh, Megha, Azcoaga-Lorenzo, Amaya, Cockburn, Neil, Wang, Jingya, Fagbamigbe, Adeniyi, Usman, Muhammad, Damase-Michel, Christine, Yau, Christopher, Kent, Lisa, Mccowan, Colin, Oreilly, Dermot, Santorelli, Gillian, Hope, Holly, Kennedy, Jonathan, Mhereeg, Mohamed, Abel, Kathryn, Eastwood, Kelly-Ann, Black, Mairead, Loane, Maria, Moss, Ngawai, Brophy, Sinead, Brocklehurst, Peter, Dolk, Helen, Nelson-Piercy, Catherine, Nirantharakumar, Krishnarajah   +29 more
openaire   +5 more sources

An interactive image segmentation method for the anatomical structures of the main olfactory bulb with micro-level resolution

Frontiers in Neuroinformatics, 2023
The main olfactory bulb is the key element of the olfactory pathway of rodents. To precisely dissect the neural pathway in the main olfactory bulb (MOB), it is necessary to construct the three-dimensional morphologies of the anatomical structures within ...
Xin Liu, Anan Li, Anan Li, Yue Luo, Shengda Bao, Tao Jiang, Xiangning Li, Xiangning Li, Jing Yuan, Jing Yuan, Zhao Feng   +10 more
doaj   +1 more source

Low-temperature resin embedding of the whole brain for various precise structures dissection

iScience, 2023
Summary: Resin embedding combined with ultra-thin sectioning has been widely used in microscopic and electron imaging to acquire precise structural information of biological tissues.
Jiaojiao Tian, Yingying Chen, Tao Jiang, Xueyan Jia, Hui Gong, Xiangning Li   +5 more
doaj   +1 more source

Statistical Analysis of Remote Health Monitoring Based IoT Security Models & Deployments From a Pragmatic Perspective

IEEE Access, 2023
Remote health monitoring-based Internet of Things (IoT) network security is a multi-domain task, that involves identification of network attack, evaluation of mitigation strategies, design of performance aware data security models, integration of privacy
Kanneboina Ashok, S. Gopikrishnan
doaj   +1 more source

Rag‐bull rider optimisation with deep recurrent neural network for epileptic seizure detection using electroencephalogram

IET Signal Processing, 2021
Electroencephalogram (EEG) signal is mostly utilised to monitor epilepsy to revitalize the close loop brain. Several classical methods devised to identify seizures rely on visual analysis of EEG signals which is a costly and complex task if channel count
Prabin Jose Johnrose, Sundaram Muniasamy, Jaffino Georgepeter   +2 more
doaj   +1 more source

A study on preterm birth predictions using physiological signals, medical health record information and low‐dimensional embedding methods

IET Cyber-systems and Robotics, 2021
Preterm births have been seen to have psychological and financial implications; current surveys suggest that amongst the various methods of preterm prediction, there is yet to exist a reliable and standard means of predicting preterm births.
Ejay Nsugbe, Oluwarotimi William Samuel, Ibrahim Sanusi, Mojisola Grace Asogbon, Guanglin Li   +4 more
doaj   +1 more source

Identification of myocardial infarction using morphological features of electrocardiogram and vectorcardiogram

IET Signal Processing, 2021
Cardiac failure, such as myocardial infarction (MI), is one of the most serious causes of mortality worldwide. MI is the sign of cardiac cell damage as a result of decreased blood oxygen level, which causes some morphological changes in the form of 12 ...
Nastaran Jafari Hafshejani, Alireza Mehridehnavi, Reza Hajian, Shabnam Boudagh, Mohaddeseh Behjati   +4 more
doaj   +1 more source

EUROmediCAT signal detection: a systematic method for identifying potential teratogenic medication [PDF]

British Journal of Clinical Pharmacology, 2016
AimsInformation about medication safety in pregnancy is inadequate. We aimed to develop a signal detection methodology to routinely identify unusual associations between medications and congenital anomalies using data collected by 15 European congenital anomaly registries.MethodsEUROmediCAT database data for 14 950 malformed foetuses/babies with first ...
Luteijn JM, Morris JK, Garne E, Given J, de Jongvan den Berg L, Addor MC, Bakker M, Barisic I, Gatt M, Klungsoyr K, LatosBielenska A, Lelong N, Nelen V, Neville A, O'Mahony M, Pierini A, Tucker D, de Walle H, Wiesel A, Loane M, Dolk H   +20 more
openaire   +5 more sources