Results 121 to 130 of about 10,088,500 (301)

Wavelet-Based Transformations for Nonlinear Signal Processing

open access: yes, 2006
Journal PaperNonlinearities are often encountered in the analysis and processing of real-world signals. We introduce two new structures for nonlinear signal processing.
Nowak, Robert David   +1 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Segmentation of gastroesophageal reflux events using a semi-U-Net architecture with 1D/2D CNNs

open access: yesScientific Reports
U-Net has gained traction in biomedical signal processing, particularly for segmenting 1D waveforms. Building on this success, we propose a U-Net-inspired architecture that integrates both 2D and 1D CNNs to effectively learn and segment gastroesophageal ...
Azra Rasouli Kenari, Hossein Rabbani
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Intraoperative cerebral perfusion monitoring with ultrafast power doppler imaging

open access: yesScientific Reports
Brain perfusion monitoring during cerebrovascular surgery is highly desirable; however, this technology is not yet available to surgeons. Our center has developed and implemented a dedicated ultrafast power Doppler imaging (UPDI) sequence along with a ...
Hamid Reza Niknejad   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Efficient Floating-Point Division for Digital Signal Processing Application [Tips & Tricks].

open access: yes, 2019
Floating-point division is an expensive operation for processors in digital signal processing (DSP). The basis of the division operation is finding the reciprocal of the divisor.
Moroz, L.V., Samotyj, V.V.
core  

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