Results 101 to 110 of about 10,088,500 (301)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Unitary Equivalence and Signal Processing
, 2006 Conference PaperThe notions of time, frequency, and scale are generalized using concepts from unitary operator theory and eigenanalysis. The result is an infinite number of new signal analysis and processing tools that are implemented simply by ...
Jones, Douglas L., Baraniuk, Richard G.
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Two dimensional signal processing for storage channels [PDF]
, 2016 Over the past decade, storage channels have undergone a steady increase in capacity. With the prediction of achieving 10 Tb/in2 areal density for magnetic recording channels in sight, the industry is pushing towards di erent technologies for storage ...
Soltanpur, Cinna
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Overlap-add Windows with Maximum Energy Concentration for Speech and Audio Processing
, 2019 Processing of speech and audio signals with time-frequency representations require windowing methods which allow perfect reconstruction of the original signal and where processing artifacts have a predictable behavior.
Bäckström, T., Tom Backstrom
core +1 more source
Acta AcusticaVirtual reality with multichannel audio playback is increasingly used in hearing aid research. The purpose of this study is to compare horizontal (2D) and periphonic (3D) rendering methods in terms of localization, minimum audible angle, and perceptual ...
Gerken Merle, Hohmann Volker, Grimm Giso
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Audio signal processing device [PDF]
, 2006 An audio signal processing device includes a signal supply for supplying speech and music signals via one or more input channels. The device further includes a signal separator for separating the speech and music signals.
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