Results 171 to 180 of about 1,132,900 (337)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Real-time vectorcardiography simulator system. [PDF]

PLoS One
Rodriguez WR, Bernal HA, Amador-Munoz DP.   +2 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Editorial: Deep learning for high-dimensional sense, non-linear signal processing and intelligent diagnosis, vol II. [PDF]

Front Psychiatry
Ke H, Cai C, Yao L, Chen D.
europepmc   +1 more source

Advancing Precision Neurology and Wearable Electrophysiology: The Pivotal Role of Medical Physicists in Signal Processing, AI, and Prognostic Modeling

Constantinos Koutsojannis, Dionysia Chrysanthakopoulou, Athanasios Fouras   +2 more
openalex   +2 more sources

Data Compression Using Neural Networks in Bio-Medical Signal Processing

, 2013
Mandavi, Prasannjit, Nilotpal Mrinal, Kalyan Chatterjee, Soura Dasgupta   +4 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Optimizing Radiographic Diagnosis Through Signal-Balanced Convolutional Models. [PDF]

J Imaging
Neemuchwala SJ, Ali RH, Abbas Q, Khan TA, Shahnaz A, Ahmed I.   +5 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

IEEE Journal of Selected Topics in Signal Processing Special Issue on Domain Enriched Learning for Medical Imaging [PDF]

, 2019

openalex   +1 more source