Results 71 to 80 of about 5,537,561 (304)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Taking into Account the History of Korean Graduate Medical Education [PDF]
, 2013 During the Japanese colonial period in the Korean Peninsula, Chosun (ethnic Korean) physicians were trained in vocational clinical schools, but Japanese physicians in medical school.
연세대학교 의과대학
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
The ontogeny and phylogeny of a medical specialty
Annals of Emergency Medicine, 1980 One. of my earliest recollections from medical school days was the mysterious phrase that "ontogeny recapitulates phylogeny." When this phrase was explained, it was clear that development of the individual organism followed many of the same stages as the evolutionary history of that group.
Department of Anesthesiology, University of Florida School of Medicine at Gainesville, Gainesville, Florida, USA ( host institution ) +1 more
openaire +3 more sources
Physician Income Prediction Errors: Sources and Implications for Behavior [PDF]
Although income expectations play a central role in many economic decisions, little is known about the sources of income prediction errors and how agents respond to income shocks.
Sean Nicholson, Nicholas S. Souleles
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 1951 This glass lantern slide features a map with an aerial view of the Medical Center campus of the Medical College of South Carolina in 1951. The map is entitled, ""Medical College of South Carolina, Medical Center, Charleston, S.C.,"" and inludes numbered ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Discover Artificial IntelligenceThis study evaluates the proficiency of ChatGPT-4 across various medical specialties and assesses its potential as a study tool for medical students preparing for the United States Medical Licensing Examination (USMLE) Step 2 and related clinical subject
Brendan P. Mackey +5 more
doaj +1 more source