Results 81 to 90 of about 160,263 (254)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Cervical Premalignant Lesions Treatment: A Randomized Controlled Trial of Cryotherapy versus Loop Excision

Journal of Medicine in Scientific Research
It was discovered that cryotherapy was just as effective as the loop electrosurgical excision process (LEEP) for removing the cervical intraepithelial neoplasia (CIN2+) lesion.
Fatma A. Dawood, Tarek M. Elhawari, Rafik I. Barakat, Naglaa A. Hussien   +3 more
doaj   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Assessing the relationship between planter fascia and planter calcaneonavicular ligament thickness in individuals suffering from planter fasciitis using musculoskeletal ultrasonography

Journal of Medicine in Scientific Research
Objective: There is uncertainty regarding how thick spring ligament is in persons with plantar fasciitis complaints, despite the fact that they exhibit laxity of this ligament.
Wessam Eissa Hamed Attia
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Effect of Mirror-Based Lateral Walking Training on Balance in Children with Hemiparesis: A Randomized Controlled Trial

Journal of Medicine in Scientific Research
Background: Cerebral palsy children with hemiparesis manifest impaired balance during static and dynamic activities which impact gait, functional activities, and quality of life.
Mohamed I. Elsepaee, Eman I. Elhadidy, Samia A. Abd Elrahman, Hesham A.E. Elghaiaty, Seham M. Abd El-Moghny   +4 more
doaj   +1 more source

Could it be hereditary angioedema?-Perspectives from different medical specialties. [PDF]

Clin Transl Allergy, 2023
Magerl M, Sala-Cunill A, Weber-Chrysochoou C, Trainotti S, Mormile I, Spadaro G.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

El trabajo de terminación de la especialidad: ¿ser o no ser?

Revista Cubana de Medicina
El trabajo de terminación de la especialidad constituye la herramienta concebida para el aprendizaje de las competencias investigativas del médico en el proceso formativo de posgrado correspondiente a la especialización.
Luis Corona Martínez
doaj