Results 171 to 180 of about 990,088 (334)

Oxidized Ti Single Atoms and Co₃O₄ with Abundant Oxygen Vacancies Collaborating with Adjacent Pd Sites for an Efficient and Stable Oxygen Reduction Reaction

open access: yesAdvanced Science, EarlyView.
ORR pathways on the surface of CP@Ti‐1 catalyst, where oxygen vacancies in Co‐oxide and oxidized Ti single atoms promote the O2 splitting while adjacent Pd sites trigger the subsequent hydration step. Abstract The current study addresses these key issues by providing the ensemble sites and creating oxygen vacancies in the oxidized Ti‐single atoms. Here
Hong‐Wei Chang   +9 more
wiley   +1 more source

Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

open access: yesAdvanced Science, EarlyView.
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su   +12 more
wiley   +1 more source

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

open access: yesAmerican Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023
Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter   +14 more
wiley   +1 more source

Atomic Layered ZnO Between Cu Nanoparticles and a PVP Polymer Layer Enable Exceptional Selectivity and Stability in Electrocatalytic CO2 Reduction to C2H4

open access: yesAdvanced Science, EarlyView.
Collaboration between Cu, ZnO, and PVP facilitates the electrochemical reduction of CO2. Abstract This study employs a chemically controlled strategy to construct a few‐atomic‐layer ZnO structure integrated with polyvinylpyrrolidone (PVP) and nanoscale metallic copper on active carbon.
Lihui Zhou   +9 more
wiley   +1 more source

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