Results 181 to 190 of about 640,680 (235)

Out of the Silence: Medical Student Depression and Suicide: A Companion Presentation

, 2008
Paula J. Clayton, Charles F. Reynolds, Sid Zisook   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Discrimination Experiences Among Medical Students.

JAMA Netw Open
Nguyen M, Venkataraman S, Abrams G, Pereira-Lima K, Fancher T, Addams AN, Moreland CJ, Boatright DH, Meeks LM.   +8 more
europepmc   +1 more source

Promoting transgender healthcare competency: simulation scenario for medical students. [PDF]

BMC Med Educ
Sobral LNE, Lima JPV, Silva AM, Monteiro LF, Britto DF, Peixoto RAC.   +5 more
europepmc   +1 more source

Relationship between religious orientation and components of emotional intelligence among medical students of Shahid Beheshti University of Medical Sciences

, 2017
Reza Tajabadi, Ali Asghar Asgharnejad Farbod   +1 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Biobanking as a research accelerator: the perspectives of medical students and interns at a saudi university. [PDF]

Front Genet
AbuOmar L, Al Eissa MM, Tamim H, Abu-Dawas S, Yaqinuddin A, Alkattan K.   +5 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

What Do Undergraduate Medical Students Value in Plastic Surgery Conferences? [PDF]

Plast Reconstr Surg Glob Open
Tagdiwala PA, Sahoo AS, Salman M, Hachem R.   +3 more
europepmc   +1 more source