Results 71 to 80 of about 541,947 (315)

Improving and expanding Medical Subject Headings (MeSH) during times of social change

The International Journal of Information, Diversity, & Inclusion
In the summer of 2020, the Latinx Caucus of the Medical Library Association focused on addressing bias in medical subject heading terminologies by establishing the Hispanic/Latinx Inclusive Terminologies Project. Two project teams were formed.
Aidy Weeks, Stephanie Fell, Katie Hoskins   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

How to Write an Effective Scientific Abstract with Keywords and MeSH Terms

Galician Medical Journal
In the scientific field, there is a critical need for the rapid and timely dissemination of findings to foster collaborations, seek funding, and establish oneself as a growing expert within their chosen domain.
Gopal Singh Charan, Raman Kalia, Maninderjit Kaur   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Predicting Basic Concepts of a Field, Based on the Factors of Oldness and Frequency Use of Subject Terms: A Case Study on Colon Cancer

مدیریت اطلاعات سلامت, 2016
Introduction: Prediction of future subjects is a necessity for policy making in science field, which is done by different variables. Accordingly, present research was conducted to predict basic concepts in the field of colon cancer based on the factor of
Mojtaba Mokhtari-Shamsi, Mohammad Tavakolizadeh-Ravari, Ebrahim Zalzadeh, Mahmoud Baghbanian   +3 more
doaj  

Strategies to optimize MEDLINE and EMBASE search strategies for anesthesiology systematic reviews. An experimental study

São Paulo Medical Journal, 2018
BACKGROUND: A high-quality electronic search is essential for ensuring accuracy and comprehensiveness among the records retrieved when conducting systematic reviews. Therefore, we aimed to identify the most efficient method for searching in both MEDLINE
Enilze de Souza Nogueira Volpato, Marluci Betini, Maria Eduarda Puga, Arnav Agarwal, Antônio José Maria Cataneo, Luciane Dias de Oliveira, Rodrigo Bazan, Leandro Gobbo Braz, José Eduardo Guimarães Pereira, Regina El Dib   +9 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

MCRWR: a new method to measure the similarity of documents based on semantic network

BMC Bioinformatics, 2022
Background Besides Boolean retrieval with medical subject headings (MeSH), PubMed provides users with an alternative way called “Related Articles” to access and collect relevant documents based on semantic similarity.
Xianwei Pan, Peng Huang, Shan Li, Lei Cui   +3 more
doaj   +1 more source

Automated Recommendation of Research Keywords from PubMed That Suggest the Molecular Mechanism Associated with Biomarker Metabolites

Metabolites, 2022
Metabolomics can help identify candidate biomarker metabolites whose levels are altered in response to disease development or drug administration. However, assessment of the underlying molecular mechanism is challenging considering it depends on the ...
Shinji Kanazawa, Satoshi Shimizu, Shigeki Kajihara, Norio Mukai, Junko Iida, Fumio Matsuda   +5 more
doaj   +1 more source