Results 251 to 260 of about 16,376,813 (311)

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Classification of Pregnancy Apps in Medical Technology Despite the Coronavirus

, 2020
Habibi MRM, Moghbeli f.
europepmc   +1 more source

Medical technology.

Minnesota medicine, 2004
openaire   +1 more source

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Medical Technology

Health Care Management Review, 1980
Technology was once considered automatically beneficial. Today the health care industry is carefully weighing the consequences as well as the advantages of medical technology. Medical technology has become a policy issue of great importance in public and private sectors.
D, Banta, C J, Behney
openaire   +2 more sources

Surveillance of Medical Technologies

Journal of Public Health Policy, 1986
Technologies from three different medical disciplines are examined in an effort to demonstrate the potential benefit of epidemiologic surveillance of health care technologies. Tubal sterilization is a common surgical procedure done in a healthy population, and a surveillance mechanism is already in place.
S B, Thacker, R L, Berkelman
openaire   +2 more sources

ASSESSING MEDICAL TECHNOLOGIES IN DEVELOPMENT

International Journal of Technology Assessment in Health Care, 2000
Our study aims to provide a practical contribution to the field of medical technology assessment within a new paradigm. This paradigm indicates the need for more comprehensive technology assessments in the development stage of a new technology.We introduce a method, based on Saaty's Analytic Hierarchy Process, which quantitatively supports discussions ...
Hummel, Marjan J.M., van Rossum, Wouter, Verkerke, Gijsbertus Jacob, Rakhorst, Gerhard   +3 more
openaire   +4 more sources

Medical Science and Technology

JAMA: The Journal of the American Medical Association, 1981
The intimate juxtaposition of science and technology—both often spoken of in the same breath—is currently threatened by those who view technological advances with mistrust. Nuclear fission and genetic engineering provoke almost as much apprehension among scientists as they do among laymen.
openaire   +2 more sources