Results 251 to 260 of about 15,500,666 (311)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Medical Technology

Health Care Management Review, 1980
Technology was once considered automatically beneficial. Today the health care industry is carefully weighing the consequences as well as the advantages of medical technology. Medical technology has become a policy issue of great importance in public and private sectors.
D, Banta, C J, Behney
openaire   +2 more sources

Surveillance of Medical Technologies

Journal of Public Health Policy, 1986
Technologies from three different medical disciplines are examined in an effort to demonstrate the potential benefit of epidemiologic surveillance of health care technologies. Tubal sterilization is a common surgical procedure done in a healthy population, and a surveillance mechanism is already in place.
S B, Thacker, R L, Berkelman
openaire   +2 more sources

ASSESSING MEDICAL TECHNOLOGIES IN DEVELOPMENT

International Journal of Technology Assessment in Health Care, 2000
Our study aims to provide a practical contribution to the field of medical technology assessment within a new paradigm. This paradigm indicates the need for more comprehensive technology assessments in the development stage of a new technology.We introduce a method, based on Saaty's Analytic Hierarchy Process, which quantitatively supports discussions ...
Hummel, Marjan J.M.   +3 more
openaire   +4 more sources

Adopting Medical Technology

Medical Decision Making, 2014
New technologies are often incorporated into clinical practice with few data on their benefits and risks. In this issue of Medical Decision Making, Gold and colleagues report results of interviews with radiation oncologists and surgeons about factors that led to adoption of one treatment, accelerated partial breast irradiation (APBI).
openaire   +2 more sources

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