Results 31 to 40 of about 955,243 (267)

Neurobiological mechanisms of ECT and TMS treatment in depression: study protocol of a multimodal magnetic resonance investigation

BMC Psychiatry, 2023
Background Noninvasive neurostimulation treatments are increasingly being used to treat major depression, which is a common cause of disability worldwide.
Leila Marie Frid, Ute Kessler, Olga Therese Ousdal, Åsa Hammar, Jan Haavik, Frank Riemer, Marco Hirnstein, Lars Ersland, Vera Jane Erchinger, Eivind Haga Ronold, Gyrid Nygaard, Petter Jakobsen, Alexander R. Craven, Berge Osnes, Renata Alisauskiene, Hauke Bartsch, Stephanie Le Hellard, Anne-Kristin Stavrum, Ketil J. Oedegaard, Leif Oltedal   +19 more
doaj   +1 more source

Simulation of blood flow characteristics based on a multicomponent non-Newtonian fluid model

工程科学学报
Visualizing characteristics of blood flow in the human body is essential for accurate diagnosis of cardiovascular diseases, analysis of pathological mechanisms, and optimization of personalized treatment.
Sijia YANG, Yuege XIONG, Xiaokun WANG, Jianguo MA, Houbin HUANG, Zhihong ZHU   +5 more
doaj   +1 more source

Vasoactive intestinal polypeptide plasma levels associated with affective symptoms and brain structure and function in healthy females

Scientific Reports, 2021
Vasoactive intestinal polypeptide (VIP) is a neuroendocrine peptide distributed throughout the human body, including the CNS, where it is particularly abundant in brain regions associated with anxiety and depression.
Rozalyn A. Simon, Nawroz Barazanji, Michael P. Jones, Olga Bednarska, Adriane Icenhour, Maria Engström, J. Paul Hamilton, Åsa V. Keita, Susanna Walter   +8 more
doaj   +1 more source

Design and user experience testing of a polygenic score report: a qualitative study of prospective users

BMC Medical Genomics, 2021
Background Polygenic scores—which quantify inherited risk by integrating information from many common sites of DNA variation—may enable a tailored approach to clinical medicine. However, alongside considerable enthusiasm, we and others have highlighted a
Deanna G. Brockman, Lia Petronio, Jacqueline S. Dron, Bum Chul Kwon, Trish Vosburg, Lisa Nip, Andrew Tang, Mary O’Reilly, Niall Lennon, Bang Wong, Kenney Ng, Katherine H. Huang, Akl C. Fahed, Amit V. Khera   +13 more
doaj   +1 more source

Multidimensional Diffusion MRI Methods With Confined Subdomains

Frontiers in Physics, 2022
Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media.
Deneb Boito, Deneb Boito, Cem Yolcu, Evren Özarslan, Evren Özarslan   +4 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Monte Carlo-based rendering of 3D echocardiography for mixed reality-guided atrial septal puncture positioning

Computer Assisted Surgery
Catheter-based intervention procedures contain complex maneuvers, and they are often performed using fluoroscopic guidance assisted by 2D and 3D echocardiography viewed on a flat screen that inherently limits depth perception. Emerging mixed reality (MR)
Dharani dhar Maddali, Håvard Solvin, Matthias Lippert, Yücel Karabiyik, Gry Dahle, Jon Mikkelsen Hjelmervik, Gabriel Kiss, Ole Jakob Elle, Henrik Brun   +8 more
doaj   +1 more source

Comparison of multiphase data from CT perfusion vs clinical 4-phase CT scans with respect to image quality, lesion detection, and LI-RADS classification in HCC patients

Heliyon, 2022
Purpose: The aim of this study was to assess the image quality and diagnostic performance of reconstructed arterial (A) and portal venous (PV) phases in computed tomography perfusion (CTP) scans compared to the corresponding phases in standard 4-phase CT
A. Mohammadi, W. Bartholmae, M. Woisetschläger   +2 more
doaj   +1 more source