Results 161 to 170 of about 30,156 (298)

Animal models in molecular biology research: Challenges, ethical imperatives, and the path to human‐relevant translation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi   +6 more
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

Assessing the levels of utilisation of WHO-recommended healthcare waste disposal practices at healthcare service delivery points in Uganda. [PDF]

open access: yesPLOS Glob Public Health
Senkubuge S   +7 more
europepmc   +1 more source

Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva

open access: yesAdvanced NanoBiomed Research, EarlyView.
A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang   +8 more
wiley   +1 more source

Sustainable Management of Medical Waste in Surgical Units: Operational Challenges and Policy Perspectives. [PDF]

open access: yesHealthcare (Basel)
Cirstea I   +6 more
europepmc   +1 more source

Embedding Chemistry and Pharmacy Into Sustainability

open access: yesAngewandte Chemie International Edition, EarlyView.
Chemistry and pharmacy provide products and processes that are indispensable for our high living standard. To understand their relationship with sustainability is important to allow them to contribute to sustainability in a sustainable manner. An integrated overview of green, circular, and sustainable chemistry and pharmacy is given and how they have t
Klaus Kümmerer
wiley   +1 more source

Addressing the disposal of unused and expired medications in Saudi households: Time to bridge the regulatory gaps. [PDF]

open access: yesPLoS One
Farooqui M   +7 more
europepmc   +1 more source

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