Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva
A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang +8 more
wiley +1 more source
Mapping the regulatory landscape for environmental sustainability of medical device practices within the European Union. [PDF]
Zarro M +4 more
europepmc +1 more source
A University-Led Take-Back Program for Pharmaceutical Waste Management: Eleven Years of Real-World Evidence on Medication Non-Use and Disposal Patterns. [PDF]
Hernández-Rangel AE +14 more
europepmc +1 more source
The Need for Medical Device Batteries to Be Designed to Be Removable. [PDF]
Brandt D, Klonoff DC, Heinemann L.
europepmc +1 more source
Behavioral nudges and targeted education as sustainability strategies to reduce hazardous waste generation in intensive care and perioperative settings: a prospective interventional study. [PDF]
Roveri G +5 more
europepmc +1 more source
Medical waste management and disposal.
openaire +1 more source
This study demonstrates the high piezo‐photocatalytic activity of solid molecular catalysts (SMCs) in the production of hydrogen peroxide from water and oxygen. Through the rational design of molecular motifs (diphenylpyridine or terpyridine) and backbone functionalities (methyl group, aliphatic amine antenna, or aromatic pyrrole unit), as well as ...
Sarah Brettschneider +7 more
wiley +1 more source
The Financial and Environmental Cost of Anaesthetic Emergency Drugs: Comparing Ampoules With Prefilled Syringes. [PDF]
Parkinson EA +6 more
europepmc +1 more source

