Results 141 to 150 of about 3,439,907 (351)
Thesis writing in medical schools: Opportunity or liability [PDF]
Gunadhar Padhi
openalex +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Turning the world upside down: Developing a tool for training about SM
About the book: Psychological and medical perspectives on sadomasochism (SM) have historically been concerned with understanding it as a form of psychopathology. In the past (but still often today) studies of SM have been concerned with extreme and most
Barker, Meg
core
Adverbials and inversion in early english scientific writing [PDF]
From a historical perspective, the English language shifted from being basically verb final in the Old English period (Traugott 1992: 274) to verb non-final from the Middle English period onwards (Fischer 1992: 371), that is, from SOV to SVO.
Romero-Barranco, Jesús
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
“It turns out I was wrong”: a thematic analysis of medical students’ reflective writing in an e-learning course on communication skills [PDF]
Laura Janssen +6 more
openalex +1 more source

