Results 241 to 250 of about 12,946 (297)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Discourses leading to diagnostic excess: an ethnopsychological study in Italian schools. [PDF]

Front Psychol
Iudici A, Caraglia C, Cottone P.
europepmc   +1 more source

Capacity building for healthcare workers on preventing and managing female genital mutilation: Impact on knowledge, attitudes, skills, and quality of care-A systematic review. [PDF]

Int J Gynaecol Obstet
Oringanje C, Oparah S, Pallitto CC, Okoro A, Otonkue M, Ovat F, Nwankwo O, Meremikwu M.   +7 more
europepmc   +1 more source

A phenomenological study on the traces of obstetric violence in women's birth experiences. [PDF]

BMC Pregnancy Childbirth
Karabulut K, Unutkan A.
europepmc   +1 more source

A problematic view of peer review; the epistemic distance of medical humanities with medicine. [PDF]

J Diabetes Metab Disord
Ravan N, Namazi H.
europepmc   +1 more source

AI-driven high-risk pregnancy prediction: balancing early detection, anxiety, and discrimination in digital public health. [PDF]

Front Public Health
Ji Q, Wang M.
europepmc   +1 more source

Health care crisis: looking beyond the obvious: Part 3: Roadmap for an equitable and sustainable health care system. [PDF]

Can Fam Physician
Pilon MD, Holland T, Moreau M, Upshur REG, Simpson C, Buchman D.   +5 more
europepmc   +1 more source

Medical literature and medical libraries.

Bulletin of the Medical Library Association, 2006
openaire   +2 more sources