Results 161 to 170 of about 6,860,665 (269)

Staying in the Unknown: Avoidance of Genetic Testing in Families With Hereditary Cancer Syndromes—A Qualitative Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To explore the experiences and challenges associated with genetic testing decisions among untested individuals from hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) families. Design Qualitative descriptive study. Methods Semi‐structured telephone interviews were conducted between 2022 and 2024 with 56 untested at‐risk ...
Ronit G. Tsemach, Elizabeth E. Half, Hagit Baris‐Feldman, Anastasia Weis, Sharon Simchoni, Sue Kim, Maria C. Katapodi, Sivia Barnoy, Efrat Dagan   +8 more
wiley   +1 more source

Trait Neuroticism and the Nocebo Effect: The Mediating Role of Side‐Effect Expectations

Journal of Personality, EarlyView.
ABSTRACT Objective Neuroticism has not only been linked to heightened negative expectations and general somatic complaints but also to increased nocebo responses following medical treatments. Since side‐effect expectations are considered a main driver of nocebo responses, we tested whether side‐effect expectations mediate the neuroticism–nocebo ...
Anton Fischer, Li‐Ching Chuang, Nick Augustat, Pia von Blanckenburg, Erik M. Mueller   +4 more
wiley   +1 more source

Tilt Table Testing in Paediatric Orthostatic Intolerance: Is 10 Min Long Enough?

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Recent cardiovascular literature suggests that orthostatic testing protocols should be tailored according to diagnostic purpose, distinguishing syncope evaluation from assessment of autonomic dysfunction in chronic orthostatic intolerance (COI).
Wonshik Choi, Sin Weon Yun
wiley   +1 more source

Medically Unexplained Symptoms: A review

, 2019
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked DownloadÓútskýrð líkamleg einkenni eru einkenni sem eiga sér engar þekktar ...
Jón Friðrik Sigurðsson, Paul Salkovskis, Sigrún Ólafsdóttir   +2 more
core  

Insula–cerebellar functional connectivity associated with somatic symptoms in mood disorders: Differential patterns and longitudinal evidence in major depressive disorder

Psychiatry and Clinical Neurosciences, EarlyView.
Aim This study aimed to identify the resting‐state functional connectivity (rsFC) of insula subregions associated with nonspecific somatic symptoms in mood disorders and to examine whether these connections are state‐dependent. Methods In Phase 1, seed‐based rsFC analyses were performed using 12 insula subregions from the Brainnetome Atlas in patients ...
Shin Hattori, Toshiharu Kamishikiryo, Alan S. R. Fermin, Yoichiro Matsumoto, Yuki Mitsuyama, Eri Itai, Yoshikazu Masuda, Go Okada   +7 more
wiley   +1 more source

Patient‐centered perspectives and feelings on peri‐implantitis and its therapy

Periodontology 2000, EarlyView.
Abstract Objectives Peri‐implantitis is a common biological complication of dental implant therapy that affects peri‐implant tissues as well as patients' psychological well‐being and oral health‐related quality of life. This review summarizes patient‐centered perspectives on peri‐implantitis, focusing on patient perception at diagnosis, treatment ...
Jungwon Lee, Young‐Chang Ko, Seung‐Ju Lee, Frank Schwarz, Ki‐Tae Koo   +4 more
wiley   +1 more source

New Insights Into Pathogenesis, Diagnostics, and Therapeutic Options for Canine Angiostrongylosis

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To provide a comprehensive overview of Angiostrongylus vasorum infection in dogs, with a particular emphasis on recent developments in the understanding of disease pathophysiology and an update on developments in diagnostic and therapeutic options.
Iris Elgueta, Daniel Lewis, Eric R. Morgan, Jenny Helm   +3 more
wiley   +1 more source

P2X3 receptor antagonism improves hindlimb blood flow during exercise in a conscious ovine model of hypertensive heart failure with preserved ejection fraction

The Journal of Physiology, EarlyView.
Abstract figure legend A preclinical large‐animal model of hypertensive heart failure with preserved ejection fraction (HFpEF) was used to examine the role of purinergic P2X3 receptor signalling during treadmill exercise. Animals were instrumented with either thoracic cardiac output and coronary flow probes or abdominal renal and hindlimb blood flow ...
Mridula Pachen, Siyi Chen, Joshua W.‐H. Chang, Audrys Pauza, Julia Shanks, Bindu George, Julian Paton, Rohit Ramchandra   +7 more
wiley   +1 more source

Case Report of a Rapidly Progressive Indolent T‐Cell Lymphoma of the Gastrointestinal Tract

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Indolent T‐cell lymphoma of the gastrointestinal tract (iTCL‐GI) is a relatively newly recognized disease entity. iTCL‐GI was first proposed by Perry et al. in 2013, before it was formally incorporated as a distinct disease category in the fifth edition of the World Health Organization Classification of Hematolymphoid Tumors: Lymphoid ...
Keitaro Shibuya, Akiko Tamura, Daiki Yafuso, Ami Kawamoto, Shuji Hibiya, Kento Takenaka, Hiromichi Shimizu, Toshimitsu Fujii, Kazuo Ohtsuka, Ryuichi Okamoto   +9 more
wiley   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source