Results 21 to 30 of about 1,804 (133)

Anatomical–Motor Level Discrepancy in Prenatal Diagnosis of Open Spinal Dysraphism: A 12‐Year Retrospective Observational Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objectives To quantify the discrepancy between anatomical and motor levels in foetuses with open spinal dysraphism and identify prenatal factors associated with this difference. We also examined associations between anatomical level and ultrasound findings. Design Retrospective observational study.
Silvia Arévalo   +8 more
wiley   +1 more source

Farmacovigilância no Brasil: a relação entre polimorfismo de fármacos, efetividade e segurança dos medicamentos

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2008
Apesar da política nacional de medicamentos propor que os mesmos tenham qualidade, eficácia e segurança, os hospitais sentinelas têm recebido notificações de queixa técnica, reações adversas e suspeita de inefetividade terapêutica de medicamentos.
H.C. Capucho   +2 more
doaj  

PE - 065 Custo-Minimização em Mieloma Múltiplo: Intercambialidade do Medicamento Lenalidomida Referência para o Similar.

open access: yesJornal de Assistência Farmacêutica e Farmacoeconomia
Introdução: O custo assistencial com tratamento das neoplasias tem gerado impacto financeiro importante nas Operadoras de Plano de Saúde (OPS). A expiração de patentes e a disponibilidade medicamentos genéricos e similares estimula a competição de ...
Paula Heberle   +5 more
doaj   +1 more source

ESTUDO ANALÍTICO E COMPARATIVO DE COMPRIMIDOS CONTENDO CITRATO DE SILDENAFILA ADQUIRIDOS NO MERCADO FORMAL E INFORMAL

open access: yesInfarma: Pharmaceutical Sciences, 2016
Citrato de sildenafila é um fármaco inibidor seletivo da enzima fosfodiesterase tipo 5 (PDE-5), restaurando naturalmente a função erétil peniana. O objetivo deste estudo foi realizar uma análise comparativa do aspecto visual, peso médio e uniformidade de
Jonathan Parisotto Peterle   +1 more
doaj   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

open access: yesAllergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz   +22 more
wiley   +1 more source

Emotional problems and dysregulation in children/youth with ADHD: predictive and moderating effects in a randomized controlled trial of methylphenidate and neurofeedback

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background Children and adolescents with Attention‐Deficit/Hyperactivity Disorder (ADHD) often show increased emotional dysregulation (ED) and internalizing emotional problems (iEP). However, the predictive and moderating role of these emotional difficulties in the treatment of ADHD—particularly regarding pharmacological (methylphenidate, MPH) and non ...
Amelie Bohner   +24 more
wiley   +1 more source

Categorizing differences in postpartum hemorrhage management and associated clinical factors

open access: yesPregnancy, Volume 2, Issue 6, November 2026.
Abstract Objective To examine whether there is variation in postpartum hemorrhage (PPH) management and whether differences are associated with patient‐level factors and delivery hospital. Methods This is a retrospective cohort study of patients delivered at ≥20 weeks of gestation at any of four hospitals within one Connecticut healthcare system, with ...
Moeun Son   +8 more
wiley   +1 more source

Estudo de perfil de dissolução dos medicamentos de referência, genérico e similar contendo cefalexina na forma farmacêutica cápsula

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2010
Com o avanço da tecnologia e das pesquisas envolvendo liberação de fármacos, modernização de testes e maior ênfase da previsibilidade de efeitos terapêuticos por meio dos testes in vitro, os testes de dissolução e os estudos de perfis de dissolução têm ...
M. Chorilli   +3 more
doaj  

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

open access: yesPediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman   +10 more
wiley   +1 more source

TriNetX LATAM Collaborative Network, an EHR Data Source in Latin America

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose In 2014, TriNetX launched a U.S.‐based federated network of health system electronic health records (EHR) that is now used in academic and industry‐sponsored studies and includes more than 250 health care organizations (HCOs) globally.
Vinicius Pinho   +4 more
wiley   +1 more source

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